Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.43 |
| ▸ | HTT | P42858 | 2/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 7/20 | 0.40 |
| ▸ | MAPT | P10636 | 7/20 | 0.40 |
| ▸ | NPC1 | O15118 | 3/20 | 0.40 |
| ▸ | GAA | P10253 | 3/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.40 |
| ▸ | RAB9A | P51151 | 2/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.39 |
| ▸ | MEN1 | O00255 | 4/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.39 |
| ▸ | HPGD | P15428 | 3/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.39 |
| ▸ | PTK2B | Q14289 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 3/20 | 0.39 |
| ▸ | GLA | P06280 | 1/20 | 0.39 |
| ▸ | KDM1A | O60341 | 1/20 | 0.39 |
| ▸ | PRKDC | P78527 | 3/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3823227 | 0.90 | SMN1; SMN2 (0.39) | SMN1; SMN2HTTKDM4EMAPTNPC1 | |
| SCHEMBL7473370 | 0.90 | MAPT (0.41) | SMN1; SMN2HTTKDM4EMAPTL3MBTL1 | |
| SCHEMBL24620639 | 0.90 | SMN1; SMN2 (0.42) | SMN1; SMN2HTTKDM4EMAPTNPC1 | |
| SCHEMBL24620629 | 0.88 | SMN1; SMN2 (0.42) | SMN1; SMN2HTTKDM4EMAPTNPC1 | |
| SCHEMBL3829545 | 0.88 | SMN1; SMN2 (0.37) | SMN1; SMN2HTTKDM4EMAPTNPC1 | |
| SCHEMBL4670962 | 0.88 | PRKDC (0.39) | SMN1; SMN2HTTKDM4EMAPTNPC1 | |
| SCHEMBL4676232 | 0.87 | PRKDC (0.39) | SMN1; SMN2HTTKDM4EMAPTNPC1 | |
| SCHEMBL2599693 | 0.87 | SMN1; SMN2 (0.37) | SMN1; SMN2HTTKDM4EMAPTNPC1 | |
| SCHEMBL4670960 | 0.87 | PRKDC (0.39) | SMN1; SMN2HTTKDM4EMAPTNPC1 | |
| SCHEMBL4677173 | 0.87 | PRKDC (0.39) | SMN1; SMN2HTTKDM4EMAPTNPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0973761-B1 | RED COLOURING HYPERCHROMIC 3H-NAPHTHO 2,1-b ]PYRANS | JAMES ROBINSON LTD (GB) | 2002-07-03 | — | — | EP | claimed |
| US-6294112-B1 | Red coloring hyperchromic 3H-naphtho[2,1-B]pyrans | JAMES ROBINSON LIMITED (GB) | 2001-09-25 | — | — | US | claimed |
| EP-0973761-A1 | RED COLOURING HYPERCHROMIC 3$i(H)-NAPHTHO 2,1-$i(b)]PYRANS | JAMES ROBINSON LIMITED (GB) | 2000-01-26 | — | — | EP | claimed |
| WO-1998045281-A1 | RED COLOURING HYPERCHROMIC 3H-NAPHTHO[2,1-b]PYRANS | JAMES ROBINSON LIMITED (GB) | 1998-10-15 | — | — | WO | claimed |
| EP-0973761-B1 | RED COLOURING HYPERCHROMIC 3H-NAPHTHO 2,1-b ]PYRANS | JAMES ROBINSON LTD (GB) | 2002-07-03 | — | — | EP | disclosed |
| US-6294112-B1 | Red coloring hyperchromic 3H-naphtho[2,1-B]pyrans | JAMES ROBINSON LIMITED (GB) | 2001-09-25 | — | — | US | disclosed |