Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 8/20 | 0.82 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.82 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.82 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.82 |
| ▸ | CA1 | P00915 | 3/20 | 0.52 |
| ▸ | CA2 | P00918 | 3/20 | 0.52 |
| ▸ | CA7 | P43166 | 2/20 | 0.52 |
| ▸ | CA9 | Q16790 | 2/20 | 0.52 |
| ▸ | CA12 | O43570 | 1/20 | 0.52 |
| ▸ | CA4 | P22748 | 1/20 | 0.52 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.52 |
| ▸ | TSHR | P16473 | 4/20 | 0.50 |
| ▸ | MAPT | P10636 | 3/20 | 0.48 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.48 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.48 |
| ▸ | IDO1 | P14902 | 1/20 | 0.47 |
| ▸ | EP300 | Q09472 | 1/20 | 0.45 |
| ▸ | KAT8 | Q9H7Z6 | 1/20 | 0.45 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.45 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Aniline SCHEMBL10386051 | 0.98 | ALDH1A1 (0.78) | ALDH1A1TDP1ADRA2BPTGS1CA1 | |
| SCHEMBL29390378 | 0.91 | — | — | |
| SCHEMBL14598 | 0.91 | — | — | |
| SCHEMBL357940 | 0.88 | ALDH1A1 (0.95) | ALDH1A1TDP1ADRA2BPTGS1CA1 | |
| Hydrochloric Acid SCHEMBL30727463 | 0.88 | ALDH1A1 (0.95) | ALDH1A1TDP1ADRA2BPTGS1CA1 | |
| Iodide SCHEMBL28354404 | 0.88 | ALDH1A1 (0.95) | ALDH1A1TDP1ADRA2BPTGS1CA1 | |
| SCHEMBL6469327 | 0.88 | ALDH1A1 (0.95) | ALDH1A1TDP1ADRA2BPTGS1CA1 | |
| Hydrochloric Acid SCHEMBL892262 | 0.88 | ALDH1A1 (0.95) | ALDH1A1TDP1ADRA2BPTGS1CA1 | |
| SCHEMBL21840888 | 0.88 | ALDH1A1 (0.95) | ALDH1A1TDP1ADRA2BPTGS1CA1 | |
| SCHEMBL7772203 | 0.88 | ALDH1A1 (0.95) | ALDH1A1TDP1ADRA2BPTGS1CA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10703746-B2 | Mutant IDH1 inhibitors useful for treating cancer | THE UNITED STATES OF AMERICA, AS REPRESENTED BY THE SECRETARY, DEPARTMENT OF HEALTH AND HUMAN SERVICES (US) | 2020-07-07 | — | — | US | disclosed |
| EP-2430099-B1 | ORGANIC COMPOUNDS | CLARIANT FINANCE BVI LTD (VG) | 2013-07-31 | — | — | EP | disclosed |
| EP-2430099-A1 | ORGANIC COMPOUNDS | Clariant Finance (BVI) Limited (VG) | 2012-03-21 | — | — | EP | disclosed |
| WO-2010130381-A1 | ORGANIC COMPOUNDS | CLARIANT INTERNATIONAL LTD (CH) | 2010-11-18 | — | — | WO | disclosed |
| EP-2251384-A1 | Pyrazolone monoazo dyes | Clariant International Ltd. (CH) | 2010-11-17 | — | — | EP | disclosed |
| EP-2251383-A1 | Organic compounds | Clariant International Ltd. (CH) | 2010-11-17 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10703746-B2 | Mutant IDH1 inhibitors useful for treating cancer | IDH1, IDH3B, IDH3A | ALDH1A1 417/4885TDP1 1693/4885ADRA2B 3979/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.