Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 4/20 | 0.59 |
| ▸ | PDGFRA | P16234 | 1/20 | 0.54 |
| ▸ | KDR | P35968 | 1/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.51 |
| ▸ | MEN1 | O00255 | 3/20 | 0.51 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.50 |
| ▸ | HPGD | P15428 | 2/20 | 0.50 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.50 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.50 |
| ▸ | RCE1 | Q9Y256 | 1/20 | 0.50 |
| ▸ | ABCG2 | Q9UNQ0 | 2/20 | 0.49 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.49 |
| ▸ | THRB | P10828 | 1/20 | 0.48 |
| ▸ | HTT | P42858 | 1/20 | 0.48 |
| ▸ | GAA | P10253 | 3/20 | 0.46 |
| ▸ | LMNA | P02545 | 3/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.46 |
| ▸ | POLB | P06746 | 1/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7484533 | 0.92 | MAPT (0.58) | MAPTPDGFRAKDRKMT2AMEN1 | |
| SCHEMBL7486681 | 0.89 | MAPT (0.74) | MAPTPDGFRAKDRKMT2AMEN1 | |
| SCHEMBL7478195 | 0.88 | MAPT (0.59) | MAPTPDGFRAKDRKMT2AMEN1 | |
| SCHEMBL7482289 | 0.88 | KDM4E (0.65) | MAPTKDRKMT2AMEN1KDM4E | |
| SCHEMBL7476747 | 0.87 | MAPT (0.62) | MAPTPDGFRAKDRKMT2AMEN1 | |
| SCHEMBL7476977 | 0.85 | KDM4E (0.53) | MAPTKMT2AMEN1KDM4EALDH1A1 | |
| SCHEMBL7478548 | 0.84 | MAPT (0.58) | MAPTPDGFRAKDRKMT2AMEN1 | |
| SCHEMBL7477799 | 0.83 | MAPT (0.53) | MAPTKMT2AMEN1KDM4EALDH1A1 | |
| SCHEMBL7472611 | 0.83 | MAPT (0.53) | MAPTKDRKMT2AMEN1KDM4E | |
| SCHEMBL1732403 | 0.83 | ABCG2 (0.57) | MAPTPDGFRAKDRKMT2AMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1229010-A1 | NOVEL DIARYLAMIDE DERIVATIVES AND USE THEREOF AS MEDICINES | Japan Energy Corporation (JP) | 2002-08-07 | — | — | EP | disclosed |