Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | S1PR1 | P21453 | 3/20 | 0.50 |
| ▸ | S1PR3 | Q99500 | 3/20 | 0.50 |
| ▸ | S1PR5 | Q9H228 | 3/20 | 0.50 |
| ▸ | S1PR4 | O95977 | 1/20 | 0.50 |
| ▸ | GBA2 | Q9HCG7 | 14/20 | 0.39 |
| ▸ | GBA1 | P04062 | 9/20 | 0.39 |
| ▸ | LSS | P48449 | 1/20 | 0.38 |
| ▸ | SPHK2 | Q9NRA0 | 1/20 | 0.38 |
| ▸ | SPHK1 | Q9NYA1 | 1/20 | 0.38 |
| ▸ | DNM1 | Q05193 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7478926 | 0.96 | S1PR1 (0.49) | S1PR1S1PR3S1PR5S1PR4GBA2 | |
| SCHEMBL7473776 | 0.85 | S1PR1 (0.52) | S1PR1S1PR3S1PR5S1PR4GBA2 | |
| SCHEMBL7475750 | 0.83 | S1PR1 (0.51) | S1PR1S1PR3S1PR5S1PR4GBA2 | |
| SCHEMBL7477717 | 0.82 | S1PR1 (0.50) | S1PR1S1PR3S1PR5S1PR4LSS | |
| SCHEMBL7472831 | 0.81 | S1PR1 (0.46) | S1PR1S1PR3S1PR5S1PR4LSS | |
| SCHEMBL7474461 | 0.81 | S1PR1 (0.45) | S1PR1S1PR3S1PR5S1PR4LSS | |
| SCHEMBL27499419 | 0.80 | S1PR1 (0.51) | S1PR1S1PR3S1PR5S1PR4SPHK2 | |
| SCHEMBL7475360 | 0.80 | S1PR1 (0.48) | S1PR1S1PR3S1PR5S1PR4SPHK2 | |
| Hydrochloric Acid SCHEMBL7483269 | 0.80 | S1PR1 (0.46) | S1PR1S1PR3S1PR5S1PR4LSS | |
| SCHEMBL7484231 | 0.79 | DNM1 (0.52) | S1PR1S1PR3S1PR5S1PR4SPHK2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0933361-B1 | 1,2-Di-substituted piperidine derivatives as hair growth promoter | SHISEIDO CO LTD (JP) | 2002-03-27 | — | — | EP | disclosed |
| US-6057337-A | USEFUL FOR CARE, IMPROVEMENT OR PREVENTION OF HAIR LOSS | SHISEIDO CO., LTD. (JP) | 2000-05-02 | — | — | US | disclosed |
| CN-1231286-A | 1,2-Di-substituted piperidine derivative, hair growth promoter and external composition for skin using the same | SHISEIDO CO LTD (JP) | 1999-10-13 | — | — | CN | disclosed |
| EP-0933361-A1 | 1,2-Di-substituted piperidine derivatives as hair growth promoter | SHISEIDO COMPANY LIMITED (JP) | 1999-08-04 | — | — | EP | disclosed |