Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | S1PR1 | P21453 | 3/20 | 0.50 |
| ▸ | S1PR3 | Q99500 | 3/20 | 0.50 |
| ▸ | S1PR5 | Q9H228 | 3/20 | 0.50 |
| ▸ | S1PR4 | O95977 | 1/20 | 0.50 |
| ▸ | DNM1 | Q05193 | 1/20 | 0.49 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.40 |
| ▸ | DGKA | P23743 | 1/20 | 0.40 |
| ▸ | NAAA | Q02083 | 2/20 | 0.38 |
| ▸ | BCHE | P06276 | 3/20 | 0.37 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.37 |
| ▸ | LSS | P48449 | 1/20 | 0.37 |
| ▸ | SPHK2 | Q9NRA0 | 2/20 | 0.36 |
| ▸ | SPHK1 | Q9NYA1 | 2/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7484231 | 0.96 | DNM1 (0.52) | S1PR1S1PR3S1PR5S1PR4DNM1 | |
| SCHEMBL27499419 | 0.94 | S1PR1 (0.51) | S1PR1S1PR3S1PR5S1PR4DNM1 | |
| SCHEMBL7472834 | 0.84 | S1PR1 (0.47) | S1PR1S1PR3S1PR5S1PR4DNM1 | |
| SCHEMBL7480502 | 0.84 | DNM1 (0.51) | DNM1DGKA | |
| Hydrochloric Acid SCHEMBL7483274 | 0.83 | S1PR1 (0.47) | S1PR1S1PR3S1PR5S1PR4DNM1 | |
| SCHEMBL7474468 | 0.82 | S1PR1 (0.46) | S1PR1S1PR3S1PR5S1PR4OPRD1 | |
| SCHEMBL7479645 | 0.82 | S1PR1 (0.50) | S1PR1S1PR3S1PR5S1PR4DNM1 | |
| SCHEMBL7474984 | 0.81 | DNM1 (0.50) | DNM1DGKANAAAEPHX2 | |
| SCHEMBL7475264 | 0.81 | DNM1 (0.44) | DNM1DGKANAAAEPHX2 | |
| SCHEMBL7478926 | 0.80 | S1PR1 (0.49) | S1PR1S1PR3S1PR5S1PR4LSS |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0933361-B1 | 1,2-Di-substituted piperidine derivatives as hair growth promoter | SHISEIDO CO LTD (JP) | 2002-03-27 | — | — | EP | disclosed |
| US-6057337-A | USEFUL FOR CARE, IMPROVEMENT OR PREVENTION OF HAIR LOSS | SHISEIDO CO., LTD. (JP) | 2000-05-02 | — | — | US | disclosed |
| EP-0933361-A1 | 1,2-Di-substituted piperidine derivatives as hair growth promoter | SHISEIDO COMPANY LIMITED (JP) | 1999-08-04 | — | — | EP | disclosed |