Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PRSS1 | P07477 | 2/20 | 0.36 |
| ▸ | PRSS2 | P07478 | 2/20 | 0.36 |
| ▸ | PRSS3 | P35030 | 2/20 | 0.36 |
| ▸ | NQO2 | P16083 | 1/20 | 0.32 |
| ▸ | C1S | P09871 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8446506 | 0.79 | SIRT3 (0.33) | — | |
| SCHEMBL6633093 | 0.75 | PRSS1 (0.36) | PRSS1PRSS2PRSS3C1S | |
| SCHEMBL4278063 | 0.72 | MCL1 (0.35) | — | |
| SCHEMBL11300864 | 0.72 | — | — | |
| SCHEMBL22325476 | 0.68 | TDP1 (0.39) | — | |
| SCHEMBL8173117 | 0.68 | NQO2 (0.31) | PRSS1PRSS2PRSS3NQO2 | |
| SCHEMBL8133375 | 0.67 | PRSS1 (0.36) | PRSS1PRSS2PRSS3C1S | |
| SCHEMBL340338 | 0.66 | — | — | |
| SCHEMBL1649841 | 0.66 | — | — | |
| SCHEMBL1649597 | 0.65 | F2 (0.38) | PRSS1PRSS2PRSS3C1S |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1194417-A1 | PHENOXY FLUOROPYRIMIDINES | BAYER AG (DE) | 2002-04-10 | — | — | EP | claimed |
| WO-2000078733-A1 | PHENOXY FLUOROPYRIMIDINES | BAYER AKTIENGESELLSCHAFT (DE) | 2000-12-28 | — | — | WO | claimed |
| EP-1194417-A1 | PHENOXY FLUOROPYRIMIDINES | BAYER AG (DE) | 2002-04-10 | — | — | EP | disclosed |
| WO-2000078733-A1 | PHENOXY FLUOROPYRIMIDINES | BAYER AKTIENGESELLSCHAFT (DE) | 2000-12-28 | — | — | WO | disclosed |