Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MCL1 | Q07820 | 2/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.33 |
| ▸ | MEN1 | O00255 | 2/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.33 |
| ▸ | AKR1B10 | O60218 | 1/20 | 0.33 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.33 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.33 |
| ▸ | DHFR | P00374 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | MPO | P05164 | 1/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.33 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.33 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.33 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.33 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.33 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.33 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8644706 | 0.85 | KDM4E (0.38) | ALDH1A1MEN1KMT2ATDP1AKR1B10 | |
| SCHEMBL11300864 | 0.83 | — | — | |
| SCHEMBL8446506 | 0.81 | SIRT3 (0.33) | ALDH1A1TDP1HSD17B10 | |
| SCHEMBL8641020 | 0.81 | TDP1 (0.38) | ALDH1A1SMN1; SMN2MEN1KMT2ATDP1 | |
| SCHEMBL7497102 | 0.79 | MEN1 (0.33) | ALDH1A1SMN1; SMN2MEN1KMT2AKDM4E | |
| SCHEMBL22325476 | 0.78 | TDP1 (0.39) | ALDH1A1TDP1LMNACYP3A4KDM4E | |
| SCHEMBL1899738 | 0.74 | HPGD (0.41) | MCL1ALDH1A1SMN1; SMN2MEN1KMT2A | |
| SCHEMBL7479727 | 0.72 | PRSS1 (0.36) | — | |
| SCHEMBL9158798 | 0.70 | TSHR (0.35) | ALDH1A1CYP1A2NAPRTSRD5A2DAO | |
| SCHEMBL4278064 | 0.70 | TDP1 (0.39) | MCL1ALDH1A1SMN1; SMN2KMT2ATDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10251392-B2 | Antimicrobial devices and compositions | AVENT, INC. (US) | 2019-04-09 | — | — | US | disclosed |
| US-20150140088-A1 | SPIROSTEROID SYSTEMS ACTING AS NEUROPROTECTIVE AND ANTI-INFLAMMATORY AGENTS | CENTRO DE INVESTIGACION Y DESARROLLO DE LOS MEDICAMENTOS (CIDEM) (CU) | 2015-05-21 | — | — | US | disclosed |
| EP-2801581-A1 | SPIROSTEROIDAL SYSTEMS HAVING NEUROACTIVE, ANTI-INFLAMMATORY EFFECTS | Centro de Investigación y Desarrollo de los Medicamentos (CIDEM) (US) | 2014-11-12 | — | — | EP | disclosed |
| US-20090035342-A1 | Antimicrobial Devices and Compositions | AVANOS MEDICAL SALES, LLC | 2009-02-05 | — | — | US | disclosed |
| EP-1781098-A2 | ANTIMICROBIAL DEVICES AND COMPOSITIONS | ACRYMED, INC. (US) | 2007-05-09 | — | — | EP | disclosed |
| WO-2006015317-A2 | ANTIMICROBIAL DEVICES AND COMPOSITIONS | ACRYMED, INC. (US) | 2006-02-09 | — | — | WO | disclosed |
| US-4551350-A | AMINO PLAST | SWS SILICONES CORPORATION (US) | 1985-11-05 | — | — | US | disclosed |
| US-4520176-A | DILUENT, DURABLE PRESS RESIN CONTAINING AN AMINOPLAST AND AN ALOEHYDE | SWS SILICONES CORPORATION (US) | 1985-05-28 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20150140088-A1 | SPIROSTEROID SYSTEMS ACTING AS NEUROPROTECTIVE AND ANTI-INFLAMMATORY AGENTS | NR3C2, GRIN3A, CYP46A1 | MCL1 4568/4885ALDH1A1 610/4885SMN1; SMN2 2544/4885 |
| US-10251392-B2 | Antimicrobial devices and compositions | AAAS, AOC1, COL14A1 | MCL1 1486/4885ALDH1A1 178/4885SMN1; SMN2 2723/4885 |
| US-20090035342-A1 | Antimicrobial Devices and Compositions | AAAS, AOC1, COL14A1 | MCL1 1486/4885ALDH1A1 178/4885SMN1; SMN2 2723/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.