Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.33 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.33 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.33 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.33 |
| ▸ | HTR2A | P28223 | 1/20 | 0.33 |
| ▸ | SCN1A | P35498 | 1/20 | 0.33 |
| ▸ | HTR2B | P41595 | 1/20 | 0.33 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.33 |
| ▸ | SCN2A | Q99250 | 1/20 | 0.33 |
| ▸ | SCN3A | Q9NY46 | 1/20 | 0.33 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.33 |
| ▸ | MMP3 | P08254 | 1/20 | 0.33 |
| ▸ | BCHE | P06276 | 3/20 | 0.33 |
| ▸ | USP2 | O75604 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | S1PR1 | P21453 | 2/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7480572 | 0.87 | PAOX (0.38) | MAPTALDH1A1MMP3BCHES1PR1 | |
| SCHEMBL7479744 | 0.74 | MAPT (0.50) | MAPTHRH3BCHEKDM4ES1PR1 | |
| SCHEMBL3308768 | 0.69 | ALDH1A1 (0.57) | MAPK1SIGMAR1ALDH1A1CYP1A2CHRM2 | |
| SCHEMBL26941298 | 0.69 | ALDH1A1 (0.57) | MAPK1SIGMAR1ALDH1A1CYP1A2CHRM2 | |
| SCHEMBL10580214 | 0.69 | ALDH1A1 (0.57) | MAPK1SIGMAR1ALDH1A1CYP1A2CHRM2 | |
| SCHEMBL18593740 | 0.69 | ALDH1A1 (0.57) | MAPK1SIGMAR1ALDH1A1CYP1A2CHRM2 | |
| SCHEMBL12120134 | 0.69 | ALDH1A1 (0.57) | MAPK1SIGMAR1ALDH1A1CYP1A2CHRM2 | |
| SCHEMBL12120133 | 0.69 | ALDH1A1 (0.57) | MAPK1SIGMAR1ALDH1A1CYP1A2CHRM2 | |
| SCHEMBL3308073 | 0.68 | ALDH1A1 (0.55) | MAPK1SIGMAR1ALDH1A1CYP1A2CHRM2 | |
| SCHEMBL10962376 | 0.68 | ALDH1A1 (0.55) | MAPK1SIGMAR1ALDH1A1CYP1A2CHRM2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0933361-B1 | 1,2-Di-substituted piperidine derivatives as hair growth promoter | SHISEIDO CO LTD (JP) | 2002-03-27 | — | — | EP | disclosed |
| US-6057337-A | USEFUL FOR CARE, IMPROVEMENT OR PREVENTION OF HAIR LOSS | SHISEIDO CO., LTD. (JP) | 2000-05-02 | — | — | US | disclosed |
| EP-0933361-A1 | 1,2-Di-substituted piperidine derivatives as hair growth promoter | SHISEIDO COMPANY LIMITED (JP) | 1999-08-04 | — | — | EP | disclosed |