Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 1/20 | 0.50 |
| ▸ | TP53 | P04637 | 2/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | BCHE | P06276 | 2/20 | 0.37 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.36 |
| ▸ | THRB | P10828 | 2/20 | 0.36 |
| ▸ | THRA | P10827 | 1/20 | 0.36 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.35 |
| ▸ | S1PR3 | Q99500 | 1/20 | 0.35 |
| ▸ | S1PR5 | Q9H228 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7480575 | 0.86 | MAPT (0.45) | MAPTTP53BCHE | |
| SCHEMBL8174166 | 0.85 | S1PR1 (0.37) | MAPTTP53MEN1KMT2AS1PR1 | |
| SCHEMBL7473656 | 0.84 | MAPT (0.45) | MAPTTP53BCHE | |
| SCHEMBL7479247 | 0.83 | MAPT (0.37) | MAPTTP53MEN1KMT2AS1PR1 | |
| SCHEMBL7480507 | 0.81 | MAPT (0.45) | MAPTTP53HRH3MEN1KMT2A | |
| SCHEMBL27517935 | 0.78 | NPC1 (0.41) | MAPTTP53MEN1KMT2AS1PR1 | |
| SCHEMBL7479738 | 0.74 | MAPT (0.39) | MAPTKDM4EBCHEHRH3THRB | |
| SCHEMBL7474801 | 0.73 | MAPT (0.47) | MAPTTP53MEN1KMT2A | |
| Hydrochloric Acid SCHEMBL7480495 | 0.73 | MAPT (0.46) | MAPTTP53MEN1KMT2A | |
| SCHEMBL7474634 | 0.72 | MAPT (0.49) | MAPTKDM4EEPHX2MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0933361-B1 | 1,2-Di-substituted piperidine derivatives as hair growth promoter | SHISEIDO CO LTD (JP) | 2002-03-27 | — | — | EP | disclosed |
| US-6057337-A | USEFUL FOR CARE, IMPROVEMENT OR PREVENTION OF HAIR LOSS | SHISEIDO CO., LTD. (JP) | 2000-05-02 | — | — | US | disclosed |
| EP-0933361-A1 | 1,2-Di-substituted piperidine derivatives as hair growth promoter | SHISEIDO COMPANY LIMITED (JP) | 1999-08-04 | — | — | EP | disclosed |