Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX5 | P09917 | 20/20 | 0.53 |
| ▸ | PTGS1 | P23219 | 3/20 | 0.45 |
| ▸ | PTGS2 | P35354 | 2/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7483918 | 0.94 | ALOX5 (0.52) | ALOX5PTGS1PTGS2 | |
| SCHEMBL7476708 | 0.92 | ALOX5 (0.55) | ALOX5PTGS1PTGS2 | |
| SCHEMBL9259689 | 0.91 | ALOX5 (0.59) | ALOX5PTGS1PTGS2 | |
| SCHEMBL7533406 | 0.91 | ALOX5 (0.51) | ALOX5PTGS1PTGS2 | |
| SCHEMBL7479485 | 0.90 | ALOX5 (0.58) | ALOX5PTGS1PTGS2 | |
| SCHEMBL7477217 | 0.90 | ALOX5 (0.58) | ALOX5PTGS1PTGS2 | |
| SCHEMBL9246552 | 0.90 | ALOX5 (0.56) | ALOX5PTGS1PTGS2 | |
| SCHEMBL7476137 | 0.89 | ALOX5 (0.57) | ALOX5PTGS1PTGS2 | |
| SCHEMBL7479920 | 0.89 | ALOX5 (0.57) | ALOX5PTGS1PTGS2 | |
| SCHEMBL7478117 | 0.89 | ALOX5 (0.57) | ALOX5PTGS1PTGS2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1250332-A1 | INHIBITORS OF INTERLEUKIN 5 GENE EXPRESSION | Abbott Laboratories (US) | 2002-10-23 | — | — | EP | claimed |
| WO-2001044223-A1 | INHIBITORS OF INTERLEUKIN 5 GENE EXPRESSION | ABBOTT LABORATORIES (US) | 2001-06-21 | — | — | WO | claimed |
| EP-1250332-A1 | INHIBITORS OF INTERLEUKIN 5 GENE EXPRESSION | Abbott Laboratories (US) | 2002-10-23 | — | — | EP | disclosed |
| WO-2001044223-A1 | INHIBITORS OF INTERLEUKIN 5 GENE EXPRESSION | ABBOTT LABORATORIES (US) | 2001-06-21 | — | — | WO | disclosed |