Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX5 | P09917 | 20/20 | 0.56 |
| ▸ | PTGS1 | P23219 | 2/20 | 0.47 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9259689 | 0.93 | ALOX5 (0.59) | ALOX5PTGS1PTGS2 | |
| SCHEMBL7477217 | 0.92 | ALOX5 (0.58) | ALOX5PTGS1PTGS2 | |
| SCHEMBL7479485 | 0.92 | ALOX5 (0.58) | ALOX5PTGS1PTGS2 | |
| SCHEMBL7478117 | 0.92 | ALOX5 (0.57) | ALOX5PTGS1PTGS2 | |
| SCHEMBL7476137 | 0.92 | ALOX5 (0.57) | ALOX5PTGS1PTGS2 | |
| SCHEMBL7479920 | 0.92 | ALOX5 (0.57) | ALOX5PTGS1PTGS2 | |
| SCHEMBL7477109 | 0.90 | ALOX5 (0.56) | ALOX5PTGS1PTGS2 | |
| SCHEMBL7479754 | 0.90 | ALOX5 (0.53) | ALOX5PTGS1PTGS2 | |
| SCHEMBL9131711 | 0.89 | ALOX5 (0.44) | ALOX5PTGS1PTGS2 | |
| SCHEMBL9131708 | 0.89 | ALOX5 (0.44) | ALOX5PTGS1PTGS2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5432194-A | Antiallergens, antinflammatory agents | ABBOTT LABORATORIES (US) | 1995-07-11 | — | — | US | disclosed |
| WO-1994026264-A1 | (4-ALKOXYPYRAN-4-YL) SUBSTITUTED ARYLALKYLARYL-, ARYLALKENYLARYL-, AND ARYLALKYNYLARYLUREA INHIBITORS OF 5-LIPOXYGENASE | ABBOTT LABORATORIES (US) | 1994-11-24 | — | — | WO | disclosed |
| US-5346914-A | Antiallergens, antiinflammatory agents | ABBOTT LABORATORIES (US) | 1994-09-13 | — | — | US | disclosed |