Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | JAK2 | O60674 | 1/20 | 0.39 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.38 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.38 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.38 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.38 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
| ▸ | FDPS | P14324 | 1/20 | 0.37 |
| ▸ | CYP2A13 | Q16696 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 2/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.36 |
| ▸ | MTOR | P42345 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14553277 | 0.86 | ALDH1A1 (0.51) | ALDH1A1KMT2APOLBCHRM2CHRM1 | |
| SCHEMBL8149708 | 0.82 | ALDH1A1 (0.46) | ALDH1A1KMT2APOLBCHRM2CHRM5 | |
| SCHEMBL14083460 | 0.77 | ALDH1A1 (0.41) | ALDH1A1KMT2APOLBCHRM2CHRM5 | |
| SCHEMBL4772963 | 0.77 | KMT2A (0.59) | ALDH1A1KMT2APOLBCHRM2CHRM5 | |
| SCHEMBL10726249 | 0.74 | SMN1; SMN2 (0.49) | ALDH1A1KMT2APOLBTSHRLMNA | |
| SCHEMBL4319831 | 0.73 | KDM4E (0.41) | ALDH1A1POLBTSHRLMNAHPGD | |
| SCHEMBL11210727 | 0.71 | KMT2A (0.55) | ALDH1A1KMT2APOLBCHRM2CHRM5 | |
| SCHEMBL15619179 | 0.71 | KMT2A (0.53) | ALDH1A1KMT2APOLBCHRM2CHRM5 | |
| SCHEMBL23204979 | 0.71 | BRD4 (0.54) | ALDH1A1KMT2APOLBKCNH2TSHR | |
| SCHEMBL8697896 | 0.70 | KMT2A (0.53) | ALDH1A1KMT2APOLBCHRM2CHRM5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20020061919-A1 | PROCESS FOR THE PREPARATION OF 1,2,3,9-TETRAHYDRO-9-METHYL-3-{(2-METHYL-1H-IMIDAZOL-1-YL)METHYL}-4H-CARBAZOL-4-ONE | HANMI PHARM. CO., LTD. (KR) | 2002-05-23 | — | — | US | disclosed |
| EP-1207160-A1 | Process for the preparation of 1,2,3,9-tetrahydro-9-methyl-3-((2-methyl-1H-imidazol-1-yl)-methyl)-4H-carbazol-4-one | Hanmi Pharm. Co., Ltd. (KR) | 2002-05-22 | — | — | EP | disclosed |
| US-6388091-B1 | IN PRESENCE OF A HALOSILANE COMPOUND; CRYSTALLIZATION, PURIFICATION | HANMI PHARM. CO., LTD. (KR) | 2002-05-14 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20020061919-A1 | PROCESS FOR THE PREPARATION OF 1,2,3,9-TETRAHYDRO-9-METHYL-3-{(2-METHYL-1H-IMIDAZOL-1-YL)METHYL}-4H-CARBAZOL-4-ONE | JAK1, CILK1, AZI2 | ALDH1A1 1316/4885KMT2A 217/4885POLB 1907/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.