Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.46 |
| ▸ | POLB | P06746 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.43 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.43 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.40 |
| ▸ | KCNH2 | Q12809 | 7/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | FDPS | P14324 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | CA12 | O43570 | 1/20 | 0.36 |
| ▸ | CA1 | P00915 | 1/20 | 0.36 |
| ▸ | CA2 | P00918 | 1/20 | 0.36 |
| ▸ | CA9 | Q16790 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8697896 | 0.84 | KMT2A (0.53) | ALDH1A1POLBKMT2ACHRM2CHRM5 | |
| SCHEMBL7479786 | 0.82 | ALDH1A1 (0.43) | ALDH1A1POLBKMT2ACHRM2CHRM5 | |
| SCHEMBL11210727 | 0.81 | KMT2A (0.55) | ALDH1A1POLBKMT2ACHRM2CHRM5 | |
| SCHEMBL14083460 | 0.80 | ALDH1A1 (0.41) | ALDH1A1POLBKMT2ACHRM2CHRM5 | |
| SCHEMBL4772963 | 0.80 | KMT2A (0.59) | ALDH1A1POLBKMT2ACHRM2CHRM5 | |
| SCHEMBL8135283 | 0.79 | KCNH2 (0.42) | ALDH1A1KMT2AKCNH2 | |
| SCHEMBL9030449 | 0.77 | CHRM2 (0.61) | ALDH1A1POLBKMT2ACHRM2CHRM5 | |
| SCHEMBL8141528 | 0.76 | KCNH2 (0.44) | ALDH1A1POLBKMT2AKCNH2TSHR | |
| SCHEMBL8135273 | 0.74 | KCNH2 (0.46) | ALDH1A1POLBKMT2AKCNH2TSHR | |
| SCHEMBL4779659 | 0.71 | ALDH1A1 (0.72) | ALDH1A1POLBKMT2AKDM4EP2RX7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0965590-A1 | Process for the preparation of formylimidazoles | LONZA A.G. (CH) | 1999-12-22 | — | — | EP | claimed |
| US-6127548-A | PREPARING OPTIONALLY SUBSTITUED 3H-IMIDAZOLE-4-CARBALDEHYDE BY PROTECTING THE 3-AMINO GROUP, THEN FORMYLATING IN PRESENCE OF AN ORGANOMETALLIC COMPOUND AND ELECTROPHILE WITH FORMYL LEAVING GROUP, DEPROTECTING WITH ACID OR STRONG BASE | LONZA AG (CH) | 2000-10-03 | — | — | US | disclosed |
| EP-0965590-A1 | Process for the preparation of formylimidazoles | LONZA A.G. (CH) | 1999-12-22 | — | — | EP | disclosed |
| EP-0965590-A1 | Process for the preparation of formylimidazoles | LONZA A.G. (CH) | 1999-12-22 | — | — | EP | disclosed |