Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F10 | P00742 | 8/20 | 0.79 |
| ▸ | PRSS1 | P07477 | 5/20 | 0.79 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.50 |
| ▸ | MAPT | P10636 | 4/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.48 |
| ▸ | HTT | P42858 | 1/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.48 |
| ▸ | LMNA | P02545 | 1/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.44 |
| ▸ | USP2 | O75604 | 1/20 | 0.44 |
| ▸ | PTK2B | Q14289 | 1/20 | 0.44 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.44 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.44 |
| ▸ | HPGD | P15428 | 2/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7482442 | 0.88 | F10 (1.00) | F10PRSS1KMT2AMAPTALDH1A1 | |
| SCHEMBL7475462 | 0.78 | F10 (0.81) | F10PRSS1KMT2AMAPTALDH1A1 | |
| SCHEMBL16383895 | 0.76 | ALDH1A1 (0.71) | F10PRSS1KMT2AMAPTALDH1A1 | |
| SCHEMBL7475225 | 0.73 | F10 (1.00) | F10PRSS1KMT2AMAPTALDH1A1 | |
| SCHEMBL7471700 | 0.72 | F10 (1.00) | F10PRSS1KMT2AMAPTALDH1A1 | |
| SCHEMBL7472609 | 0.72 | F10 (0.72) | F10PRSS1KMT2AMAPTALDH1A1 | |
| SCHEMBL23034650 | 0.71 | HPGD (0.72) | KMT2AALDH1A1HTTSMN1; SMN2KDM4E | |
| SCHEMBL7475473 | 0.71 | F10 (1.00) | F10PRSS1KMT2AMAPTALDH1A1 | |
| SCHEMBL22895496 | 0.70 | HPGD (0.71) | ALDH1A1HTTSMN1; SMN2KDM4EHPGD | |
| SCHEMBL264516 | 0.70 | HPGD (0.76) | KMT2AALDH1A1SMN1; SMN2LMNAKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1183235-A2 | INHIBITORS OF FACTOR Xa | COR THERAPEUTICS, INC. (US) | 2002-03-06 | — | — | EP | disclosed |
| WO-2000071510-A2 | INHIBITORS OF FACTOR Xa | COR THERAPEUTICS, INC. (US) | 2000-11-30 | — | — | WO | disclosed |