Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR6 | P50406 | 7/20 | 0.47 |
| ▸ | CA2 | P00918 | 1/20 | 0.47 |
| ▸ | ADRB1 | P08588 | 3/20 | 0.45 |
| ▸ | PKM | P14618 | 2/20 | 0.45 |
| ▸ | MCOLN3 | Q8TDD5 | 2/20 | 0.45 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.45 |
| ▸ | STAT3 | P40763 | 1/20 | 0.43 |
| ▸ | HTR7 | P34969 | 3/20 | 0.42 |
| ▸ | HTR1A | P08908 | 3/20 | 0.42 |
| ▸ | HTR3A | P46098 | 3/20 | 0.42 |
| ▸ | HTR2A | P28223 | 2/20 | 0.42 |
| ▸ | HTR5A | P47898 | 2/20 | 0.42 |
| ▸ | HTR3E | A5X5Y0 | 2/20 | 0.42 |
| ▸ | HTR3B | O95264 | 2/20 | 0.42 |
| ▸ | HTR3D | Q70Z44 | 2/20 | 0.42 |
| ▸ | HTR3C | Q8WXA8 | 2/20 | 0.42 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.42 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.42 |
| ▸ | NCF1 | P14598 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL7485902 | 0.99 | HTR6 (0.46) | HTR6CA2ADRB1PKMMCOLN3 | |
| SCHEMBL2884249 | 0.81 | ADRB1 (0.53) | HTR6ADRB1MCOLN3STAT3HTR7 | |
| Hydrochloric Acid SCHEMBL4524195 | 0.79 | ADRB1 (0.51) | HTR6ADRB1MCOLN3STAT3HTR7 | |
| SCHEMBL14356049 | 0.78 | ADRB1 (0.49) | HTR6ADRB1MCOLN3HTR7HTR1A | |
| SCHEMBL14356051 | 0.78 | MCOLN3 (0.64) | HTR6PKMMCOLN3L3MBTL1DRD3 | |
| SCHEMBL14356053 | 0.77 | ADRB1 (0.47) | HTR6ADRB1MCOLN3STAT3HTR7 | |
| SCHEMBL7833448 | 0.74 | CHEK1 (0.50) | L3MBTL1 | |
| SCHEMBL4468998 | 0.74 | ADRB1 (0.51) | HTR6ADRB1HTR7HTR1AHTR3A | |
| SCHEMBL5558969 | 0.74 | MCOLN3 (0.57) | HTR6CA2PKMMCOLN3L3MBTL1 | |
| SCHEMBL14356050 | 0.73 | PARP14 (0.45) | HTR6ADRB1STAT3HTR1AHTR3A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1117651-A1 | NEW BIS-BENZIMIDAZOLES | Bayer Aktiengesellschaft (DE) | 2001-07-25 | — | — | EP | disclosed |
| WO-2000020401-A1 | NEW BIS-BENZIMIDAZOLES | BAYER AKTIENGESELLSCHAFT (DE) | 2000-04-13 | — | — | WO | disclosed |