SCHEMBL748032

SCHEMBL748032

CCOCCN1CCN(C)C1=O

nearest known ligand 0.42

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
SCN9A Q15858 1/20 0.34
POLB P06746 1/20 0.33
TSHR P16473 1/20 0.32
ALDH1A1 P00352 1/20 0.32
PKM P14618 1/20 0.32
PER2 O15055 1/20 0.31
CRY2 Q49AN0 1/20 0.31
CYP2D6 P10635 1/20 0.31
CYP2C19 P33261 1/20 0.31
ADORA2A P29274 2/20 0.31
ADORA2B P29275 2/20 0.31
PDE4A P27815 1/20 0.31
PDE4B Q07343 1/20 0.31
PDE4C Q08493 1/20 0.31
PDE4D Q08499 1/20 0.31
HSD17B10 Q99714 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL749725 0.90 POLB (0.38) POLBTSHRALDH1A1PKMCYP2D6
SCHEMBL6940560 0.85 POLB (0.36) POLBTSHRALDH1A1PKMPER2
SCHEMBL8394448 0.81 CYP1A1 (0.37) POLBTSHRALDH1A1
SCHEMBL751330 0.80 ALDH1A1 (0.38) SCN9AALDH1A1PER2CRY2HSD17B10
Ether SCHEMBL18546875 0.79 PIK3CD (0.32)
SCHEMBL19657257 0.78 SCN9A (0.33) SCN9APER2CRY2
SCHEMBL750534 0.77 L3MBTL1 (0.39) POLBALDH1A1PER2CRY2
SCHEMBL24118782 0.76 SCN9A (0.31) SCN9A
SCHEMBL8393277 0.75 POLB (0.38) SCN9APOLBTSHRALDH1A1CYP2D6
SCHEMBL329639 0.74

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 70 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4894409-A BLEND OR AMINO GROUP CONTAINING DIENE POLYMER AND SILICA FILLER NONCRACKING, WEAR RESISTANCE JAPAN SYNTHETIC RUBBER CO., LTD. (JP) 1990-01-16 US claimed
US-20250340706-A1 LAMINATE AND METHOD FOR PRODUCING LAMINATE ASAHI KASEI KABUSHIKI KAISHA (JP) 2025-11-06 US disclosed
US-12404403-B2 Polyphenylene ether-based resin composition and molded article ASAHI KASEI KABUSHIKI KAISHA (JP) 2025-09-02 US disclosed
CN-120059051-A Process for producing modified conjugated diene polymer, conjugated diene polymer composition, and tire 中化学科学技术研究有限公司 2025-05-30 CN disclosed
EP-4538038-A1 LAMINATE AND METHOD FOR MANUFACTURING LAMINATE Asahi Kasei Kabushiki Kaisha (JP) 2025-04-16 EP disclosed
EP-3778654-B1 METHOD FOR PRODUCING CONJUGATED DIENE RUBBER ZEON CORP (JP) 2025-02-26 EP disclosed
CN-119343241-A Laminate and method for producing laminate 旭化成株式会社 2025-01-21 CN disclosed
CN-114729180-B Polyphenylene ether resin composition and molded article 旭化成株式会社 2024-08-27 CN disclosed
CN-117545808-A A resin composition method for producing resin composition and molded article 旭化成株式会社 2024-02-09 CN disclosed
US-11873364-B2 Method for producing conjugated diene rubber ZEON CORPORATION (JP) 2024-01-16 US disclosed
EP-1054026-A1 BUTADIENE POLYMERS AND PROCESS FOR PRODUCING CONJUGATED DIENE POLYMERS JAPAN as Represented by DIRECTOR GENERAL OF AGENCY OF INDUSTRIAL SCIENCE AND TECHNOLOGY (JP) 2000-11-22 EP disclosed
EP-0609010-B1 A process for producing a diolefin polymer or copolymer and a rubber composition containing such a diolefin polymer or copolymer BRIDGESTONE CORP (JP) 2000-03-15 EP disclosed
EP-0572792-B1 Tire tread composition BRIDGESTONE CORP (JP) 1998-12-09 EP disclosed
US-5527860-A PROMOTER IS REACTION PRODUCT OF A SECONDARY AMINE AND ORGANOLITHIUM COMPOUND OR ALCOHOL AND A LITHIUM ALKOXIDE JAPAN SYNTHETIC RUBBER CO., LTD. (JP) 1996-06-18 US disclosed
EP-0609010-A2 A process for producing a diolefin polymer or copolymer and a rubber composition containing such a diolefin polymer or copolymer BRIDGESTONE CORPORATION (JP) 1994-08-03 EP disclosed
EP-0572792-A1 Tire tread composition BRIDGESTONE CORPORATION (JP) 1993-12-08 EP disclosed
US-5248722-A Functionalized elastomer, oxidized carbon black, reduced hysteresis BRIDGESTONE CORPORATION (JP) 1993-09-28 US disclosed
US-5017636-A Also containing polyisoprene, natural rubber, butadiene-styrene copolymer, wear and heat resistance, resilience JAPAN SYNTHETIC RUBBER CO., LTD. (JP) 1991-05-21 US disclosed
US-4929679-A BUTADIENE-STYRENE COPOLYMERS BLENDS WITH NATURAL RUBBERS OR POLYISOPRENE, WEAR RESISTANCE NIPPON ZEON CO., LTD. (JP) 1990-05-29 US disclosed
US-4894409-A BLEND OR AMINO GROUP CONTAINING DIENE POLYMER AND SILICA FILLER NONCRACKING, WEAR RESISTANCE JAPAN SYNTHETIC RUBBER CO., LTD. (JP) 1990-01-16 US disclosed