Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 9/20 | 0.62 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.62 |
| ▸ | HSD17B10 | Q99714 | 4/20 | 0.62 |
| ▸ | HPGD | P15428 | 3/20 | 0.62 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.62 |
| ▸ | RCE1 | Q9Y256 | 1/20 | 0.62 |
| ▸ | MAPT | P10636 | 6/20 | 0.56 |
| ▸ | GAA | P10253 | 3/20 | 0.56 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.53 |
| ▸ | LMNA | P02545 | 3/20 | 0.53 |
| ▸ | POLB | P06746 | 1/20 | 0.53 |
| ▸ | TSHR | P16473 | 2/20 | 0.52 |
| ▸ | CA12 | O43570 | 1/20 | 0.52 |
| ▸ | CA1 | P00915 | 1/20 | 0.52 |
| ▸ | CA2 | P00918 | 1/20 | 0.52 |
| ▸ | CA9 | Q16790 | 1/20 | 0.52 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.51 |
| ▸ | MEN1 | O00255 | 4/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.50 |
| ▸ | ABCG2 | Q9UNQ0 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7478023 | 0.88 | KDM4E (0.63) | KDM4EALDH1A1HSD17B10HPGDNPSR1 | |
| SCHEMBL7480760 | 0.86 | LMNA (0.63) | KDM4EALDH1A1HSD17B10HPGDNPSR1 | |
| SCHEMBL7472532 | 0.85 | KDM4E (0.63) | KDM4EALDH1A1HSD17B10HPGDNPSR1 | |
| SCHEMBL7478736 | 0.85 | MAPT (0.57) | KDM4EALDH1A1HSD17B10HPGDNPSR1 | |
| SCHEMBL7479701 | 0.81 | KMT2A (0.69) | KDM4EALDH1A1HSD17B10HPGDMAPT | |
| SCHEMBL7478733 | 0.81 | ALDH1A1 (0.70) | KDM4EALDH1A1HSD17B10HPGDNPSR1 | |
| SCHEMBL7484357 | 0.80 | ALDH1A1 (0.62) | KDM4EALDH1A1HSD17B10HPGDNPSR1 | |
| SCHEMBL7485732 | 0.80 | MAPK1 (0.57) | KDM4EALDH1A1HSD17B10HPGDMAPT | |
| SCHEMBL7475994 | 0.80 | KDM4E (0.69) | KDM4EALDH1A1HSD17B10HPGDMAPT | |
| SCHEMBL7476908 | 0.80 | MAPT (0.60) | KDM4EALDH1A1HSD17B10HPGDNPSR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1229010-A1 | NOVEL DIARYLAMIDE DERIVATIVES AND USE THEREOF AS MEDICINES | Japan Energy Corporation (JP) | 2002-08-07 | — | — | EP | disclosed |