Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 2/20 | 0.45 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.39 |
| ▸ | MAPT | P10636 | 2/20 | 0.39 |
| ▸ | NPC1 | O15118 | 2/20 | 0.39 |
| ▸ | RAB9A | P51151 | 2/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.38 |
| ▸ | KCNA5 | P22460 | 1/20 | 0.36 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.36 |
| ▸ | PKM | P14618 | 1/20 | 0.35 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.35 |
| ▸ | ATM | Q13315 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7479429 | 0.83 | HPGD (0.49) | HPGDHSD17B10ALDH1A1MEN1KMT2A | |
| SCHEMBL7483116 | 0.79 | ALDH1A1 (0.44) | HPGDHSD17B10ALDH1A1SMN1; SMN2MAPT | |
| SCHEMBL7487235 | 0.75 | HPGD (0.47) | HPGDHSD17B10ALDH1A1MEN1KMT2A | |
| SCHEMBL7486396 | 0.75 | SMN1; SMN2 (0.41) | HPGDHSD17B10ALDH1A1KMT2AL3MBTL1 | |
| SCHEMBL11389834 | 0.71 | ALDH1A1 (0.49) | HPGDHSD17B10ALDH1A1MEN1KMT2A | |
| SCHEMBL949944 | 0.71 | KCNA5 (0.47) | ALDH1A1MEN1KMT2ASMN1; SMN2GAA | |
| SCHEMBL15196339 | 0.70 | KCNA5 (0.46) | ALDH1A1MEN1KMT2ASMN1; SMN2GAA | |
| SCHEMBL7483635 | 0.69 | HSD17B10 (0.47) | HPGDHSD17B10ALDH1A1MEN1KMT2A | |
| SCHEMBL12125558 | 0.68 | KCNA5 (0.45) | ALDH1A1MEN1KMT2ASMN1; SMN2GAA | |
| SCHEMBL20658225 | 0.68 | KMT2A (0.61) | ALDH1A1KMT2ASMN1; SMN2LMNAKCNH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1999020618-A1 | THIADIAZOLES AMIDES USEFUL AS ANTIINFLAMMATORY AGENTS | ACTIVE BIOTECH AB (SE) | 1999-04-29 | — | — | WO | disclosed |
| WO-1999020617-A1 | ANTIINFLAMMATORY THIADIAZOLYL UREAS WHICH ACT AS LFA-1 AND MAC-1 INHIBITORS | ACTIVE BIOTECH AB (SE) | 1999-04-29 | — | — | WO | disclosed |