Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ELANE | P08246 | 3/20 | 0.33 |
| ▸ | GPR84 | Q9NQS5 | 1/20 | 0.33 |
| ▸ | DAO | P14920 | 2/20 | 0.33 |
| ▸ | MAP1LC3B | Q9GZQ8 | 1/20 | 0.32 |
| ▸ | MAP1LC3A | Q9H492 | 1/20 | 0.32 |
| ▸ | CEL | P19835 | 1/20 | 0.31 |
| ▸ | LNPEP | Q9UIQ6 | 8/20 | 0.31 |
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6174784 | 0.81 | MEN1 (0.35) | GPR84LNPEP | |
| SCHEMBL6178325 | 0.80 | — | — | |
| SCHEMBL6175205 | 0.80 | HTR2B (0.46) | DAO | |
| SCHEMBL6175129 | 0.74 | ELANE (0.33) | ELANECELHCAR2 | |
| SCHEMBL9197301 | 0.74 | ELANE (0.34) | ELANEGPR84CELHCAR2 | |
| SCHEMBL6173939 | 0.71 | MAPT (0.31) | — | |
| SCHEMBL6174712 | 0.70 | HPGD (0.33) | — | |
| SCHEMBL9198707 | 0.69 | CEL (0.41) | GPR84CEL | |
| SCHEMBL6177695 | 0.67 | CYP2C9 (0.38) | ELANE | |
| SCHEMBL6174860 | 0.65 | ELANE (0.33) | ELANE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0668860-B1 | PYRAN-2-ONES AND 5,6-DIHYDROPYRAN-2-ONES USEFUL FOR TREATING HIV AND OTHER RETROVIRUSES | UPJOHN CO (US) | 2002-09-11 | — | — | EP | claimed |