Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 5/20 | 0.62 |
| ▸ | MAPT | P10636 | 4/20 | 0.62 |
| ▸ | NPC1 | O15118 | 4/20 | 0.62 |
| ▸ | MEN1 | O00255 | 2/20 | 0.62 |
| ▸ | HTT | P42858 | 2/20 | 0.62 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.62 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.62 |
| ▸ | ABCB1 | P08183 | 2/20 | 0.62 |
| ▸ | ABCG2 | Q9UNQ0 | 2/20 | 0.62 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.61 |
| ▸ | GAA | P10253 | 1/20 | 0.59 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.57 |
| ▸ | LMNA | P02545 | 2/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7488009 | 0.83 | SMN1; SMN2 (0.74) | RAB9AMAPTNPC1KMT2AALDH1A1 | |
| SCHEMBL15701276 | 0.78 | MAPT (0.55) | RAB9AMAPTNPC1MEN1HTT | |
| SCHEMBL4651782 | 0.76 | ALDH1A1 (0.60) | RAB9AMAPTNPC1MEN1HTT | |
| SCHEMBL28455181 | 0.74 | MAPT (0.61) | RAB9AMAPTNPC1MEN1HTT | |
| SCHEMBL25412903 | 0.73 | CYP1A2 (0.64) | RAB9AMAPTNPC1MEN1HTT | |
| SCHEMBL5153509 | 0.73 | USP2 (0.61) | RAB9AMAPTNPC1MEN1HTT | |
| SCHEMBL724711 | 0.73 | ALDH1A1 (0.62) | RAB9AMAPTNPC1MEN1HTT | |
| SCHEMBL30494127 | 0.73 | ALDH1A1 (0.62) | RAB9AMAPTNPC1MEN1HTT | |
| SCHEMBL13200063 | 0.72 | FLT3 (0.60) | RAB9AMAPTNPC1SMN1; SMN2GAA | |
| SCHEMBL3307141 | 0.72 | MAPT (0.57) | RAB9AMAPTNPC1MEN1HTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2000061631-A1 | MODIFIED PENTAPEPTIDE ANTAGONISTS OF THE ATRIAL NATRIURETIC PEPTIDE CLEARANCE RECEPTOR | ASTRAZENECA AB (SE) | 2000-10-19 | — | — | WO | disclosed |