SCHEMBL724711

SCHEMBL724711

CCOC(=O)c1cnc2ccccc2n1

nearest known ligand 0.69

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 5/20 0.62
MEN1 O00255 3/20 0.62
KMT2A Q03164 3/20 0.62
NPC1 O15118 3/20 0.62
RAB9A P51151 3/20 0.62
MAPT P10636 3/20 0.62
ABCB1 P08183 1/20 0.62
HTT P42858 1/20 0.62
ABCG2 Q9UNQ0 1/20 0.62
SMN1; SMN2 Q16637 3/20 0.58
KDM4E B2RXH2 1/20 0.58
CASP3 P42574 1/20 0.58
SENP7 Q9BQF6 1/20 0.58
CYP1A2 P05177 2/20 0.57
HPGD P15428 1/20 0.57
ALOX15 P16050 1/20 0.57
HSD17B10 Q99714 1/20 0.57
CYP2C9 P11712 1/20 0.56
HIF1A Q16665 1/20 0.56
GRN P28799 1/20 0.49

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30494127 1.00 ALDH1A1 (0.62) ALDH1A1MEN1KMT2ANPC1RAB9A
Pyrrole SCHEMBL28577580 0.93 ALDH1A1 (0.56) ALDH1A1MEN1KMT2ANPC1RAB9A
SCHEMBL10356523 0.88 ALDH1A1 (0.54) ALDH1A1MEN1KMT2ANPC1RAB9A
SCHEMBL28286266 0.83 RAB9A (0.51) ALDH1A1MEN1KMT2ANPC1RAB9A
SCHEMBL21865083 0.82 ALDH1A1 (0.48) ALDH1A1MEN1KMT2ANPC1RAB9A
SCHEMBL4651782 0.82 ALDH1A1 (0.60) ALDH1A1MEN1KMT2ANPC1RAB9A
SCHEMBL4277314 0.81 ALDH1A1 (0.62) ALDH1A1MEN1KMT2ASMN1; SMN2KDM4E
SCHEMBL6616258 0.81 KMT2A (0.60) ALDH1A1MEN1KMT2ANPC1RAB9A
SCHEMBL1681081 0.81 CYP1A2 (0.58) ALDH1A1MEN1KMT2ANPC1RAB9A
SCHEMBL1209894 0.81 GABRA2 (0.52) ALDH1A1MEN1KMT2ANPC1RAB9A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 76 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-10224485-B2 Process for preparing a crystalline organic semiconductor material BASF SE (DE) 2019-03-05 US claimed
US-20170012208-A1 ORGANIC SEMICONDUCTOR FORMULATIONS USINVEST LLC 2017-01-12 US claimed
US-5939568-A Accelerated catalysis of olefinic epoxidations THE SCRIPPS RESEARCH INSTITUTE (US) 1999-08-17 US claimed
WO-1998033786-A9 ACCELERATED CATALYSIS OF OLEFINIC EPOXIDATIONS 1998-12-30 WO claimed
WO-1998033786-A1 ACCELERATED CATALYSIS OF OLEFINIC EPOXIDATIONS THE SCRIPPS RESEARCH INSTITUTE (US) 1998-08-06 WO claimed
EP-0070518-A2 Imidazoquinoxaline compounds RORER INTERNATIONAL (OVERSEAS) INC. (US) 1983-01-26 EP claimed
EP-3183250-B1 PROCESS FOR PREPARING CRYSTALLINE ORGANIC SEMICONDUCTOR MATERIAL CLAP CO LTD (KR) 2023-10-04 EP disclosed
WO-2023138599-A1 AROMATIC FUSED RING NAV1.8 INHIBITOR, AND USE THEREOF 成都康弘药业集团股份有限公司 2023-07-27 WO disclosed
CN-116462662-A Aromatic ring Nav1.8 inhibitor and application thereof 成都康弘药业集团股份有限公司 2023-07-21 CN disclosed
EP-3183757-B1 ORGANIC SEMICONDUCTOR COMPOSITION COMPRISING LIQUID MEDIUM CLAP CO LTD (KR) 2022-05-04 EP disclosed
US-10454037-B2 Organic semiconductor composition comprising a liquid medium BASF SE (DE) 2019-10-22 US disclosed
US-10224485-B2 Process for preparing a crystalline organic semiconductor material BASF SE (DE) 2019-03-05 US disclosed
US-10043978-B2 Organic semiconductor formulations FLEXTERRA, INC. (US) 2018-08-07 US disclosed
WO-1998033786-A1 ACCELERATED CATALYSIS OF OLEFINIC EPOXIDATIONS THE SCRIPPS RESEARCH INSTITUTE (US) 1998-08-06 WO disclosed
CN-1036003-C A process for preparing (1H-azol-1-ylmethyl) substituted quinoxaline derivatives JANSSEN PHARMACEUTICA NV (BE) 1997-10-01 CN disclosed
EP-0724908-A1 Noble metal raney catalysts and preparation of hydrogenated compounds using such catalysts SHOWA DENKO KABUSHIKI KAISHA (JP) 1996-08-07 EP disclosed
CN-1106005-A A process for preparing (1H-azol-1-ylmethyl) substituted quinoxaline derivatives JANSSEN PHARMACEUTICA NV (BE) 1995-08-02 CN disclosed
CN-1106004-A A process for preparing (1H-azol-1-ylmethyl) substituted quinazoline derivatives JANSSEN PHARMACEUTICA NV (BE) 1995-08-02 CN disclosed
CN-1042912-A (1H-oxazol-1-ylmethyl) substituted quinoline, quinazoline or quinoxaline derivatives JANSSEN PHARMACEUTICA NV (BE) 1990-06-13 CN disclosed
EP-0070518-A2 Imidazoquinoxaline compounds RORER INTERNATIONAL (OVERSEAS) INC. (US) 1983-01-26 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-10454037-B2 Organic semiconductor composition comprising a liquid medium CRY1, NEFM, OR10J3 ALDH1A1 4298/4885MEN1 2472/4885KMT2A 4158/4885
US-10224485-B2 Process for preparing a crystalline organic semiconductor material STOM, SPOP, TTR ALDH1A1 4757/4885MEN1 722/4885KMT2A 3227/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.