Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR1A | P08908 | 3/20 | 0.46 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.37 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.35 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.35 |
| ▸ | HTR6 | P50406 | 3/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.33 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.33 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31051992 | 0.81 | HTR1A (0.50) | HTR1AADRB1CYP2C9CYP2C19ALDH1A1 | |
| SCHEMBL31051799 | 0.80 | HTR1A (0.52) | HTR1AADRB1CYP2C9CYP2C19ALDH1A1 | |
| SCHEMBL31052148 | 0.80 | HTR1A (0.52) | HTR1AADRB1CYP2C9CYP2C19ALDH1A1 | |
| SCHEMBL1455855 | 0.80 | ADRB1 (0.59) | HTR1AADRB1CYP2C9HTR6CYP3A4 | |
| Hydrochloric Acid SCHEMBL4171025 | 0.79 | ADRB1 (0.57) | HTR1AADRB1CYP2C9HTR6CYP3A4 | |
| SCHEMBL7821489 | 0.75 | HTR1A (0.46) | HTR1A | |
| SCHEMBL7473402 | 0.75 | ADRB1 (0.65) | HTR1AADRB1ALDH1A1LMNACYP3A4 | |
| SCHEMBL4174667 | 0.72 | MEN1 (0.44) | HTR1AALDH1A1LMNA | |
| SCHEMBL7807803 | 0.72 | HTR1A (0.62) | HTR1A | |
| SCHEMBL7818467 | 0.72 | HTR1A (0.47) | HTR1AALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0982305-B1 | Indane-1-ol derivatives, process for their preparation and pharmaceutical compositions containing them | SERVIER LAB (FR) | 2002-03-06 | — | — | EP | disclosed |
| EP-0982305-A1 | Indane-1-ol derivatives, process for their preparation and pharmaceutical compositions containing them | ADIR ET COMPAGNIE (FR) | 2000-03-01 | — | — | EP | disclosed |