Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 2/20 | 0.37 |
| ▸ | RAB9A | P51151 | 2/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | ESR1 | P03372 | 1/20 | 0.31 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.31 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.31 |
| ▸ | CNR1 | P21554 | 1/20 | 0.30 |
| ▸ | CNR2 | P34972 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Benzotriazole SCHEMBL7904688 | 0.95 | NPC1 (0.36) | NPC1RAB9ALMNAPOLBCYP3A4 | |
| Benzotriazole SCHEMBL7901441 | 0.90 | NPC1 (0.33) | NPC1RAB9ALMNAPOLB | |
| SCHEMBL29354035 | 0.88 | NPC1 (0.46) | NPC1RAB9ALMNAPOLBALDH1A1 | |
| SCHEMBL29903 | 0.88 | NPC1 (0.46) | NPC1RAB9ALMNAPOLBALDH1A1 | |
| SCHEMBL5086788 | 0.85 | NPC1 (0.34) | NPC1RAB9ALMNAPOLBCNR1 | |
| SCHEMBL5510301 | 0.84 | NPC1 (0.41) | NPC1RAB9ALMNAPOLBALDH1A1 | |
| Benzotriazole SCHEMBL7895570 | 0.84 | NPC1 (0.33) | NPC1RAB9A | |
| SCHEMBL6558920 | 0.84 | NPC1 (0.45) | NPC1RAB9ALMNAPOLBALDH1A1 | |
| SCHEMBL30393631 | 0.84 | NPC1 (0.45) | NPC1RAB9ALMNAPOLBALDH1A1 | |
| Benzotriazole SCHEMBL3915546 | 0.83 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0309402-B2 | N-substituted hindered amine stabilizers | CIBA SC HOLDING AG (CH) | 2002-06-12 | — | — | EP | claimed |
| EP-0309402-B1 | N-substituted hindered amine stabilizers | CIBA GEIGY AG (CH) | 1995-01-11 | — | — | EP | claimed |
| US-20170313043-A1 | CURABLE EPOXY COMPOSITION AND FILM, LAMINATED FILM, PREPREG, LAMINATE, CURED ARTICLE, AND COMPOSITE ARTICLE OBTAINED USING SAME | ZEON CORPORATION (US) | 2017-11-02 | — | — | US | disclosed |