Benzotriazole

Benzotriazole

SCHEMBL7901441

CC(C)(C)CC(C)(C)c1cc(-n2nc3ccccc3n2)c(O)c(C(C)(C)c2ccccc2)c1.c1ccc2[nH]nnc2c1

nearest known ligand 0.33

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Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
NPC1 O15118 2/20 0.33
RAB9A P51151 2/20 0.33
POLB P06746 1/20 0.31
LMNA P02545 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Benzotriazole SCHEMBL7895570 0.93 NPC1 (0.33) NPC1RAB9A
Benzotriazole SCHEMBL3915546 0.93
Benzotriazole SCHEMBL7480928 0.90 NPC1 (0.37) NPC1RAB9APOLBLMNA
Benzotriazole SCHEMBL7904688 0.89 NPC1 (0.36) NPC1RAB9APOLBLMNA
SCHEMBL29353178 0.89 NPC1 (0.40) NPC1RAB9APOLBLMNA
SCHEMBL76991 0.89 NPC1 (0.40) NPC1RAB9APOLBLMNA
Benzotriazole SCHEMBL28936996 0.87 ACSS2 (0.30)
Bisoctrizole SCHEMBL26123807 0.85 NPC1 (0.35) NPC1RAB9APOLBLMNA
Benzotriazole SCHEMBL4615801 0.83 NPC1 (0.36) NPC1RAB9APOLBLMNA
SCHEMBL22080467 0.82 SHBG (0.36) NPC1RAB9APOLBLMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-110944957-B Heat-resistant radiation-curable coating for optical fibers 科思创(荷兰)有限公司 2022-07-08 CN disclosed
CN-113165971-A Filled radiation curable compositions for coating optical fibers and coatings produced therefrom MS控股有限公司 2021-07-23 CN disclosed
CN-106574142-B Monochromatic actinic radiation curable coatings for optical fibers 帝斯曼知识产权资产管理有限公司 2020-12-11 CN disclosed
US-6268415-B1 POLYMERS AND STABILIZERS FOR ENHANCED STABILITY CIBA SPECIALTY CHEMICALS CORPORATION 2001-07-31 US disclosed