Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | S1PR1 | P21453 | 3/20 | 0.48 |
| ▸ | S1PR3 | Q99500 | 3/20 | 0.48 |
| ▸ | S1PR5 | Q9H228 | 3/20 | 0.48 |
| ▸ | S1PR4 | O95977 | 1/20 | 0.44 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.40 |
| ▸ | DNM2 | P50570 | 4/20 | 0.36 |
| ▸ | SPHK2 | Q9NRA0 | 2/20 | 0.35 |
| ▸ | SPHK1 | Q9NYA1 | 2/20 | 0.35 |
| ▸ | CXCR4 | P61073 | 6/20 | 0.34 |
| ▸ | GNAI3 | P08754 | 1/20 | 0.34 |
| ▸ | GNAO1 | P09471 | 1/20 | 0.34 |
| ▸ | GNAI1 | P63096 | 1/20 | 0.34 |
| ▸ | DNM1 | Q05193 | 1/20 | 0.34 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7475360 | 0.95 | S1PR1 (0.48) | S1PR1S1PR3S1PR5S1PR4OPRD1 | |
| SCHEMBL7478926 | 0.81 | S1PR1 (0.49) | S1PR1S1PR3S1PR5S1PR4SPHK2 | |
| SCHEMBL7474468 | 0.79 | S1PR1 (0.46) | S1PR1S1PR3S1PR5S1PR4OPRD1 | |
| SCHEMBL7471137 | 0.78 | MEN1 (0.45) | — | |
| SCHEMBL7479645 | 0.78 | S1PR1 (0.50) | S1PR1S1PR3S1PR5S1PR4SPHK2 | |
| SCHEMBL8198867 | 0.77 | DPP4 (0.39) | S1PR1S1PR3S1PR5 | |
| SCHEMBL14509683 | 0.76 | OPRD1 (0.43) | S1PR1S1PR3S1PR5S1PR4OPRD1 | |
| SCHEMBL7474461 | 0.76 | S1PR1 (0.45) | S1PR1S1PR3S1PR5S1PR4OPRD1 | |
| SCHEMBL7478605 | 0.76 | S1PR1 (0.44) | S1PR1S1PR3S1PR5S1PR4OPRD1 | |
| SCHEMBL7480020 | 0.75 | MEN1 (0.47) | DNM1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0933361-B1 | 1,2-Di-substituted piperidine derivatives as hair growth promoter | SHISEIDO CO LTD (JP) | 2002-03-27 | — | — | EP | disclosed |
| US-6057337-A | USEFUL FOR CARE, IMPROVEMENT OR PREVENTION OF HAIR LOSS | SHISEIDO CO., LTD. (JP) | 2000-05-02 | — | — | US | disclosed |
| EP-0933361-A1 | 1,2-Di-substituted piperidine derivatives as hair growth promoter | SHISEIDO COMPANY LIMITED (JP) | 1999-08-04 | — | — | EP | disclosed |