SCHEMBL7481310

SCHEMBL7481310

O=C1CC(O)CC(C=Cc2c(C3CC3)nc3ccccc3c2-c2ccc(F)cc2)O1

nearest known ligand 0.75

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
HMGCR P04035 10/20 0.74
RXRA P19793 1/20 0.58

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9301248 1.00 HMGCR (0.74) HMGCRRXRA
SCHEMBL247234 1.00 HMGCR (0.74) HMGCRRXRA
SCHEMBL247233 1.00 HMGCR (0.74) HMGCRRXRA
SCHEMBL7481306 1.00 HMGCR (0.74) HMGCRRXRA
SCHEMBL10049194 0.89 HMGCR (0.60) HMGCRRXRA
SCHEMBL13847591 0.89 HMGCR (0.66) HMGCR
SCHEMBL13994086 0.88 HMGCR (0.61) HMGCR
SCHEMBL13524825 0.88 HMGCR (0.65) HMGCR
SCHEMBL13994087 0.88 HMGCR (0.65) HMGCR
SCHEMBL14207592 0.88 HMGCR (0.61) HMGCR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0747341-B1 PROCESS FOR PRODUCING OPTICALLY ACTIVE MEVALONOLACTONE COMPOUNDS DAICEL CHEM (JP) 2002-05-22 EP disclosed
EP-0747341-A1 PROCESS FOR PRODUCING OPTICALLY ACTIVE MEVALONOLACTONE COMPOUND DAICEL CHEMICAL INDUSTRIES, LTD. (JP) 1996-12-11 EP disclosed