Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.45 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.45 |
| ▸ | HPGD | P15428 | 1/20 | 0.45 |
| ▸ | TSHR | P16473 | 1/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.45 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.45 |
| ▸ | POLB | P06746 | 2/20 | 0.45 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.45 |
| ▸ | APEX1 | P27695 | 1/20 | 0.45 |
| ▸ | RECQL | P46063 | 1/20 | 0.45 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.45 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.45 |
| ▸ | TP53 | P04637 | 2/20 | 0.44 |
| ▸ | MAPT | P10636 | 3/20 | 0.44 |
| ▸ | BCL2 | P10415 | 3/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.44 |
| ▸ | MDM2 | Q00987 | 2/20 | 0.44 |
| ▸ | MCL1 | Q07820 | 2/20 | 0.44 |
| ▸ | GAA | P10253 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7237443 | 0.91 | POLB (0.53) | KDM4EALDH1A1HPGDPOLBTDP1 | |
| SCHEMBL15057593 | 0.84 | MYC (0.52) | ALDH1A1SMN1; SMN2POLBTDP1APEX1 | |
| SCHEMBL15057277 | 0.81 | KMT2A (0.52) | ALDH1A1SMN1; SMN2L3MBTL1TP53MAPT | |
| SCHEMBL3096202 | 0.81 | CA9 (0.57) | TP53MAPTKMT2AGAA | |
| SCHEMBL3299372 | 0.74 | KMT2A (0.68) | ALDH1A1POLBTDP1TP53MAPT | |
| SCHEMBL7231829 | 0.74 | TP53 (0.49) | KDM4EALDH1A1HPGDHSD17B10POLB | |
| SCHEMBL1877549 | 0.74 | TP53 (0.63) | KDM4EALDH1A1SMN1; SMN2HSD17B10POLB | |
| SCHEMBL18017546 | 0.73 | KMT2A (0.57) | KDM4EALDH1A1POLBTDP1TP53 | |
| SCHEMBL7229599 | 0.73 | POLB (0.62) | KDM4EALDH1A1HPGDSMN1; SMN2HSD17B10 | |
| SCHEMBL930228 | 0.73 | ALDH1A1 (0.59) | KDM4EALDH1A1CYP1A2HPGDTSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1999032454-A9 | NITROGEN CONTAINING HETEROAROMATICS WITH ORTHO-SUBSTITUTED P1'S AS FACTOR XA INHIBITORS | DU PONT PHARM CO (US) | 2001-05-31 | — | — | WO | disclosed |