Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LOXL2 | Q9Y4K0 | 2/20 | 0.64 |
| ▸ | MAOB | P27338 | 3/20 | 0.47 |
| ▸ | TAAR1 | Q96RJ0 | 2/20 | 0.43 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.41 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | CACNA1B | Q00975 | 1/20 | 0.38 |
| ▸ | IDO1 | P14902 | 1/20 | 0.38 |
| ▸ | AGXT | P21549 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28591631 | 0.80 | LOXL2 (0.53) | LOXL2MAOBSMN1; SMN2CACNA1B | |
| SCHEMBL21063 | 0.80 | — | — | |
| Benzylamine SCHEMBL7734905 | 0.79 | LOXL2 (0.61) | LOXL2MAOBTAAR1POLBSMN1; SMN2 | |
| SCHEMBL28097374 | 0.78 | LOXL2 (0.94) | LOXL2MAOBTAAR1HRH3IDO1 | |
| Ammonia Solution, Strong SCHEMBL4750128 | 0.78 | LOXL2 (0.94) | LOXL2MAOBTAAR1HRH3IDO1 | |
| Hydrochloric Acid SCHEMBL3830237 | 0.78 | LOXL2 (0.94) | LOXL2MAOBTAAR1HRH3IDO1 | |
| Hydrochloric Acid SCHEMBL3847812 | 0.78 | LOXL2 (0.94) | LOXL2MAOBTAAR1HRH3IDO1 | |
| Bromide SCHEMBL31513710 | 0.78 | LOXL2 (0.94) | LOXL2MAOBTAAR1HRH3IDO1 | |
| Iodide SCHEMBL20838270 | 0.78 | LOXL2 (0.94) | LOXL2MAOBTAAR1HRH3IDO1 | |
| Hydrochloric Acid SCHEMBL6153650 | 0.75 | LOXL2 (0.89) | LOXL2MAOBTAAR1HRH3IDO1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1218384-A4 | TETRACYCLIC BENZIMIDAZOLE DERIVATIVES AND COMBINATORIAL LIBRARIES THEREOF | LION BIOSCIENCE AG (DE) | 2002-11-20 | — | — | EP | disclosed |
| EP-1218384-A1 | TETRACYCLIC BENZIMIDAZOLE DERIVATIVES AND COMBINATORIAL LIBRARIES THEREOF | LION Bioscience AG (DE) | 2002-07-03 | — | — | EP | disclosed |
| WO-2001023392-A1 | TETRACYCLIC BENZIMIDAZOLE DERIVATIVES AND COMBINATORIAL LIBRARIES THEREOF | LION BIOSCIENCE AG (DE) | 2001-04-05 | — | — | WO | disclosed |