Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 5/20 | 0.67 |
| ▸ | TP53 | P04637 | 1/20 | 0.67 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.60 |
| ▸ | NTRK1 | P04629 | 2/20 | 0.60 |
| ▸ | NTRK2 | Q16620 | 2/20 | 0.60 |
| ▸ | RAB9A | P51151 | 7/20 | 0.53 |
| ▸ | NPC1 | O15118 | 6/20 | 0.53 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.53 |
| ▸ | LMNA | P02545 | 3/20 | 0.53 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.53 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.53 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.53 |
| ▸ | HTT | P42858 | 1/20 | 0.53 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.53 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.53 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.53 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.53 |
| ▸ | MEN1 | O00255 | 2/20 | 0.53 |
| ▸ | ABL1 | P00519 | 2/20 | 0.51 |
| ▸ | SRC | P12931 | 2/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7426870 | 0.87 | NTRK1 (0.64) | MAPTTP53KMT2ANTRK1NTRK2 | |
| SCHEMBL7476339 | 0.84 | MAPT (0.67) | MAPTTP53KMT2ANTRK1NTRK2 | |
| SCHEMBL7477859 | 0.83 | MAPT (0.64) | MAPTTP53KMT2ANTRK1NTRK2 | |
| SCHEMBL7481013 | 0.81 | MAPT (0.63) | MAPTTP53KMT2ANTRK1NTRK2 | |
| SCHEMBL7480423 | 0.79 | MAPT (0.66) | MAPTTP53KMT2ANTRK1NTRK2 | |
| SCHEMBL7478008 | 0.79 | MAPT (0.63) | MAPTTP53KMT2ANTRK1NTRK2 | |
| SCHEMBL7478376 | 0.78 | MAPT (0.65) | MAPTTP53KMT2ANTRK1NTRK2 | |
| SCHEMBL7478572 | 0.78 | MAPT (0.57) | MAPTTP53KMT2ANTRK1NTRK2 | |
| SCHEMBL7479597 | 0.76 | GLS (0.55) | MAPTTP53KMT2ARAB9ANPC1 | |
| SCHEMBL7482445 | 0.75 | MAPT (0.63) | MAPTTP53KMT2ANTRK1NTRK2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1999020617-A1 | ANTIINFLAMMATORY THIADIAZOLYL UREAS WHICH ACT AS LFA-1 AND MAC-1 INHIBITORS | ACTIVE BIOTECH AB (SE) | 1999-04-29 | — | — | WO | disclosed |