Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.50 |
| ▸ | MAPT | P10636 | 4/20 | 0.50 |
| ▸ | NPC1 | O15118 | 3/20 | 0.50 |
| ▸ | RAB9A | P51151 | 3/20 | 0.50 |
| ▸ | HPGD | P15428 | 1/20 | 0.50 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.48 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.48 |
| ▸ | RELA | Q04206 | 1/20 | 0.48 |
| ▸ | MEN1 | O00255 | 5/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.47 |
| ▸ | PRMT1 | Q99873 | 1/20 | 0.47 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.45 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.45 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.45 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.45 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.44 |
| ▸ | GAA | P10253 | 1/20 | 0.44 |
| ▸ | PKM | P14618 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7398968 | 0.87 | PRMT1 (0.52) | SMN1; SMN2ALDH1A1MAPTNPC1HPGD | |
| SCHEMBL7394619 | 0.87 | PRMT1 (0.52) | SMN1; SMN2ALDH1A1MAPTNPC1HPGD | |
| SCHEMBL7433039 | 0.83 | MEN1 (0.42) | SMN1; SMN2MAPTNPC1MEN1KMT2A | |
| SCHEMBL7394697 | 0.81 | PRMT1 (0.45) | SMN1; SMN2MAPTNPC1RAB9AMEN1 | |
| SCHEMBL7388689 | 0.80 | ENPP1 (0.51) | SMN1; SMN2MAPTNPC1RAB9AMEN1 | |
| SCHEMBL7395666 | 0.79 | NAMPT (0.49) | SMN1; SMN2ALDH1A1RAB9AMEN1KMT2A | |
| SCHEMBL7390973 | 0.79 | ENPP1 (0.53) | SMN1; SMN2ALDH1A1MAPTNPC1RAB9A | |
| SCHEMBL7395377 | 0.78 | PRMT1 (0.48) | SMN1; SMN2ALDH1A1MAPTNPC1RAB9A | |
| SCHEMBL7394539 | 0.77 | KMT2A (0.50) | SMN1; SMN2MAPTNPC1RAB9AHPGD | |
| SCHEMBL7396365 | 0.76 | NPC1 (0.51) | NPC1RAB9AHPGDMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2002006215-A1 | 3-ARYLSULFONYL-2-HYDROXY-2-METHYLPROPANOIC ACID DERIVATES | PHARMACIA ITALIA S.P.A. (IT) | 2002-01-24 | — | — | WO | disclosed |