Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ENPP1 | P22413 | 2/20 | 0.51 |
| ▸ | ENPP2 | Q13822 | 2/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.47 |
| ▸ | NPC1 | O15118 | 2/20 | 0.45 |
| ▸ | HTT | P42858 | 1/20 | 0.45 |
| ▸ | RAB9A | P51151 | 1/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.45 |
| ▸ | MAPT | P10636 | 3/20 | 0.45 |
| ▸ | PRMT1 | Q99873 | 2/20 | 0.45 |
| ▸ | CA12 | O43570 | 1/20 | 0.44 |
| ▸ | CA1 | P00915 | 1/20 | 0.44 |
| ▸ | CA9 | Q16790 | 1/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 5/20 | 0.43 |
| ▸ | ENPP3 | O14638 | 1/20 | 0.42 |
| ▸ | APAF1 | O14727 | 1/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.42 |
| ▸ | CASP3 | P42574 | 1/20 | 0.42 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.42 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7394697 | 0.91 | PRMT1 (0.45) | ENPP1ENPP2KMT2ANPC1RAB9A | |
| SCHEMBL7396188 | 0.91 | NPC1 (0.46) | KMT2ANPC1HTTRAB9ASMN1; SMN2 | |
| SCHEMBL7394619 | 0.91 | PRMT1 (0.52) | ENPP1ENPP2KMT2ANPC1SMN1; SMN2 | |
| SCHEMBL7398968 | 0.91 | PRMT1 (0.52) | ENPP1ENPP2KMT2ANPC1SMN1; SMN2 | |
| SCHEMBL7394539 | 0.91 | KMT2A (0.50) | KMT2ANPC1HTTRAB9ASMN1; SMN2 | |
| SCHEMBL7396365 | 0.82 | NPC1 (0.51) | ENPP1ENPP2KMT2ANPC1RAB9A | |
| SCHEMBL7395377 | 0.82 | PRMT1 (0.48) | ENPP1ENPP2KMT2ANPC1RAB9A | |
| SCHEMBL7483398 | 0.80 | SMN1; SMN2 (0.50) | ENPP1KMT2ANPC1HTTRAB9A | |
| SCHEMBL7433039 | 0.80 | MEN1 (0.42) | KMT2ANPC1SMN1; SMN2MAPTPRMT1 | |
| SCHEMBL7396547 | 0.79 | TRPV1 (0.48) | KMT2ANPC1RAB9ASMN1; SMN2MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2002006215-A1 | 3-ARYLSULFONYL-2-HYDROXY-2-METHYLPROPANOIC ACID DERIVATES | PHARMACIA ITALIA S.P.A. (IT) | 2002-01-24 | — | — | WO | claimed |
| WO-2002006215-A1 | 3-ARYLSULFONYL-2-HYDROXY-2-METHYLPROPANOIC ACID DERIVATES | PHARMACIA ITALIA S.P.A. (IT) | 2002-01-24 | — | — | WO | disclosed |