Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRNA7 | P36544 | 2/20 | 0.44 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 2/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | USP2 | O75604 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.40 |
| ▸ | ADRA1D | P25100 | 1/20 | 0.40 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.40 |
| ▸ | ADRA1B | P35368 | 1/20 | 0.40 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL7480209 | 0.99 | CHRNA7 (0.44) | CHRNA7PDE4BLMNAKDM4EUSP2 | |
| SCHEMBL7477683 | 0.81 | CHRNA7 (0.62) | CHRNA7PDE4BLMNAKDM4EUSP2 | |
| SCHEMBL7478156 | 0.70 | CHRNA7 (0.42) | CHRNA7LMNAKDM4EUSP2ALDH1A1 | |
| SCHEMBL7475383 | 0.68 | KMT2A (0.46) | CHRNA7LMNAKDM4EUSP2ALDH1A1 | |
| Hydrochloric Acid SCHEMBL7481541 | 0.67 | MEN1 (0.39) | CHRNA7LMNAKDM4EUSP2ALDH1A1 | |
| SCHEMBL3041638 | 0.67 | REV1 (0.74) | CHRNA7PDE4BKDM4EALDH1A1TSHR | |
| SCHEMBL7478927 | 0.66 | HRH3 (0.56) | CHRNA7 | |
| SCHEMBL8793776 | 0.65 | REV1 (0.70) | CHRNA7PDE4BHSD17B10NPC1RAB9A | |
| SCHEMBL7477137 | 0.65 | SLC6A2 (0.35) | — | |
| SCHEMBL17538296 | 0.64 | PLK1 (0.45) | CHRNA7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0950056-B1 | N-(PYRIDINYLAMINO)ISOINDOLINES AND RELATED COMPOUNDS | AVENTIS PHARMA INC (US) | 2002-09-18 | — | — | EP | claimed |
| EP-0950056-A2 | N-(PYRIDINYLAMINO)ISOINDOLINES AND RELATED COMPOUNDS | HOECHST MARION ROUSSEL, INC. (US) | 1999-10-20 | — | — | EP | claimed |
| WO-1998029407-A2 | N-(PYRIDINYLAMINO)ISOINDOLINES FOR TREATING ALZHEIMER'S AND DEPRESSION | HOECHST MARION ROUSSEL, INC. (US) | 1998-07-09 | — | — | WO | claimed |