Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CDK1 | P06493 | 4/20 | 0.34 |
| ▸ | CCNB1 | P14635 | 4/20 | 0.34 |
| ▸ | CCNA2 | P20248 | 3/20 | 0.34 |
| ▸ | CDK2 | P24941 | 3/20 | 0.34 |
| ▸ | CCNA1 | P78396 | 3/20 | 0.34 |
| ▸ | PIN1 | Q13526 | 1/20 | 0.34 |
| ▸ | ADORA3 | P0DMS8 | 3/20 | 0.33 |
| ▸ | ADORA2A | P29274 | 3/20 | 0.33 |
| ▸ | POLA1 | P09884 | 3/20 | 0.32 |
| ▸ | XDH | P47989 | 6/20 | 0.32 |
| ▸ | PAK1 | Q13153 | 1/20 | 0.32 |
| ▸ | HTT | P42858 | 1/20 | 0.32 |
| ▸ | NCOA1 | Q15788 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
| ▸ | NCOA3 | Q9Y6Q9 | 1/20 | 0.32 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.31 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.31 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.31 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7488939 | 0.92 | ADORA3 (0.38) | CDK1CCNB1CCNA2CDK2CCNA1 | |
| SCHEMBL7490134 | 0.90 | PAK1 (0.39) | CDK1CCNB1CCNA2CDK2CCNA1 | |
| SCHEMBL7491723 | 0.89 | CDK1 (0.39) | CDK1CCNB1CCNA2CDK2CCNA1 | |
| SCHEMBL7491987 | 0.86 | CDK1 (0.33) | CDK1CCNB1CCNA2CDK2CCNA1 | |
| SCHEMBL7496566 | 0.74 | ADORA3 (0.32) | ADORA3ADORA2AXDH | |
| SCHEMBL7496538 | 0.73 | PDK2 (0.30) | — | |
| SCHEMBL7486537 | 0.70 | — | — | |
| SCHEMBL9045356 | 0.69 | ALDH1A1 (0.30) | — | |
| SCHEMBL2867175 | 0.69 | ALDH1A1 (0.46) | CDK1CCNB1CCNA2CDK2CCNA1 | |
| SCHEMBL11077322 | 0.69 | ALDH1A1 (0.50) | CDK1CCNB1CCNA2CDK2CCNA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0915093-B1 | AMIDE DERIVATIVES | OTSUKA PHARMA CO LTD (JP) | 2002-11-27 | — | — | EP | disclosed |
| EP-0915093-A1 | AMIDE DERIVATIVES | OTSUKA PHARMACEUTICAL FACTORY, INC. (JP) | 1999-05-12 | — | — | EP | disclosed |