Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SRD5A2 | P31213 | 2/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | RAB9A | P51151 | 1/20 | 0.43 |
| ▸ | VNN1 | O95497 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 2/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | CNR1 | P21554 | 1/20 | 0.40 |
| ▸ | CNR2 | P34972 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | NR4A1 | P22736 | 1/20 | 0.39 |
| ▸ | GALR3 | O60755 | 1/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8001938 | 0.88 | SRD5A2 (0.54) | SRD5A2MAPK1RAB9AMAPTSMN1; SMN2 | |
| SCHEMBL7829968 | 0.87 | HSP90AB1 (0.46) | KMT2AMEN1RAB9AMAPTTDP1 | |
| SCHEMBL27457488 | 0.86 | SMN1; SMN2 (0.47) | SRD5A2MAPK1KMT2ARAB9AVNN1 | |
| SCHEMBL7990297 | 0.86 | SRD5A2 (0.41) | SRD5A2KMT2AMEN1RAB9AMAPT | |
| SCHEMBL7998751 | 0.85 | VNN1 (0.42) | MAPK1KMT2AMEN1VNN1MAPT | |
| SCHEMBL8002841 | 0.83 | NAPRT (0.43) | KMT2AMEN1RAB9AVNN1MAPT | |
| SCHEMBL7838560 | 0.83 | KMT2A (0.56) | KMT2AMEN1RAB9AMAPTSMN1; SMN2 | |
| SCHEMBL7998602 | 0.82 | RECQL (0.36) | SRD5A2RAB9AVNN1SMN1; SMN2ALDH1A1 | |
| SCHEMBL8000191 | 0.81 | CCR9 (0.39) | SRD5A2KMT2AVNN1KDM4E | |
| SCHEMBL7483341 | 0.80 | MAPT (0.46) | SRD5A2MAPK1KMT2AMEN1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0831088-B1 | 1,2,4-Triazine-3,5-dione derivatives as anticoccidial agents | TAKEDA SCHERING PLOUGH ANIMAL (JP) | 2002-11-27 | — | — | EP | disclosed |
| US-5985875-A | USEFUL AS ANTI-PROTOZOAL AGENTS | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1999-11-16 | — | — | US | disclosed |
| EP-0831088-A1 | 1,2,4-Triazine-3,5-dione derivatives as anticoccidial agents | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1998-03-25 | — | — | EP | disclosed |