Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 4/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.46 |
| ▸ | POLB | P06746 | 1/20 | 0.46 |
| ▸ | HTT | P42858 | 3/20 | 0.46 |
| ▸ | GAA | P10253 | 3/20 | 0.46 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.46 |
| ▸ | VCAM1 | P19320 | 2/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.44 |
| ▸ | LMNA | P02545 | 3/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.44 |
| ▸ | NPC1 | O15118 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.43 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.43 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 2/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.43 |
| ▸ | SRD5A2 | P31213 | 1/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7840421 | 0.90 | CYP1A2 (0.51) | MAPTMAPK1TDP1POLBHTT | |
| SCHEMBL8002481 | 0.89 | SRD5A2 (0.49) | MAPTMAPK1TDP1POLBHTT | |
| SCHEMBL7989865 | 0.86 | MAPT (0.43) | MAPTMAPK1TDP1POLBHTT | |
| SCHEMBL8005114 | 0.85 | MAPT (0.44) | MAPTMAPK1TDP1POLBHTT | |
| SCHEMBL7841868 | 0.84 | MAPK1 (0.54) | MAPTMAPK1TDP1POLBHTT | |
| SCHEMBL8001948 | 0.84 | L3MBTL1 (0.44) | MAPTMAPK1TDP1POLBHTT | |
| SCHEMBL8000281 | 0.83 | MEN1 (0.46) | MAPTMAPK1TDP1POLBHTT | |
| SCHEMBL7922602 | 0.80 | HGFAC (0.42) | MAPTMAPK1TDP1POLBHTT | |
| SCHEMBL7484185 | 0.80 | SRD5A2 (0.44) | MAPTMAPK1TDP1HTTALDH1A1 | |
| SCHEMBL27457488 | 0.78 | SMN1; SMN2 (0.47) | MAPK1HTTSMN1; SMN2CYP2C9CYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1128141-C | 1, 2, 4 -triazine -3, 5 -dione derivatives, their production and use thereof | TAKEDA SHERING PLOUR ANIMAL HE (JP) | 2003-11-19 | — | — | CN | disclosed |
| EP-0831088-B1 | 1,2,4-Triazine-3,5-dione derivatives as anticoccidial agents | TAKEDA SCHERING PLOUGH ANIMAL (JP) | 2002-11-27 | — | — | EP | disclosed |
| US-5985875-A | USEFUL AS ANTI-PROTOZOAL AGENTS | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1999-11-16 | — | — | US | disclosed |
| EP-0831088-A1 | 1,2,4-Triazine-3,5-dione derivatives as anticoccidial agents | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1998-03-25 | — | — | EP | disclosed |
| CN-1175577-A | 1, 2, 4 -triazine -3, 5 -dione derivatives, their production and use thereof | TAKEDA CHEMICAL INDUSTRIES LTD (JP) | 1998-03-11 | — | — | CN | disclosed |