Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ITGB3 | P05106 | 18/20 | 0.44 |
| ▸ | ITGA2B | P08514 | 11/20 | 0.44 |
| ▸ | ITGAV | P06756 | 15/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4023860 | 0.86 | ITGB3 (0.57) | ITGB3ITGA2BITGAV | |
| SCHEMBL5155928 | 0.86 | ITGB3 (0.57) | ITGB3ITGA2BITGAV | |
| SCHEMBL4024909 | 0.86 | ITGB3 (0.57) | ITGB3ITGA2BITGAV | |
| SCHEMBL337310 | 0.82 | ITGB3 (0.48) | ITGB3ITGA2BITGAV | |
| SCHEMBL7668371 | 0.82 | ITGB3 (0.58) | ITGB3ITGA2BITGAV | |
| SCHEMBL7078802 | 0.77 | ITGB3 (0.49) | ITGB3ITGA2BITGAV | |
| SCHEMBL5972894 | 0.74 | VDR (0.49) | ITGB3ITGA2BITGAV | |
| SCHEMBL5972553 | 0.74 | ITGB3 (0.68) | ITGB3ITGA2BITGAV | |
| SCHEMBL6677340 | 0.74 | ITGB3 (0.68) | ITGB3ITGA2BITGAV | |
| SCHEMBL6677335 | 0.74 | ITGB3 (0.68) | ITGB3ITGA2BITGAV |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6495545-B1 | ANTIOSTEOPOROTIC, ANTIRESTENOTIC, ANTICARCINOGENIC AND ANTIATHEROSCLEROTIC ACTIVITY | BAYER AKTIENGESELLSCHAFT (DE) | 2002-12-17 | — | — | US | disclosed |
| US-6339083-B1 | FOR THERAPY OF OSTEOPOROSIS, RESTENOSIS, CARCINOSES AND/OR ARTERIOSCLEROSIS | BAYER AKTIENGESELLSCHAFT (DE) | 2002-01-15 | — | — | US | disclosed |
| EP-1140927-A1 | 1,4-BENZODIAZEPINONE DERIVATIVES AND THEIR USE AS INTEGRIN ANTAGONISTS | Bayer Aktiengesellschaft (DE) | 2001-10-10 | — | — | EP | disclosed |
| WO-2000035917-A1 | 1,4-BENZODIAZEPINONE DERIVATIVES AND THEIR USE AS INTEGRIN ANTAGONISTS | BAYER AKTIENGESELLSCHAFT (DE) | 2000-06-22 | — | — | WO | disclosed |