Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 4/20 | 0.63 |
| ▸ | SETD7 | Q8WTS6 | 1/20 | 0.59 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.55 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.55 |
| ▸ | KMT2A | Q03164 | 7/20 | 0.55 |
| ▸ | MEN1 | O00255 | 5/20 | 0.55 |
| ▸ | RXFP1 | Q9HBX9 | 2/20 | 0.54 |
| ▸ | MAPT | P10636 | 3/20 | 0.54 |
| ▸ | HTT | P42858 | 2/20 | 0.53 |
| ▸ | G6PD | P11413 | 2/20 | 0.53 |
| ▸ | GAA | P10253 | 2/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7481623 | 0.84 | KMT2A (0.60) | LMNAALDH1A1SMN1; SMN2KMT2AMEN1 | |
| SCHEMBL7486616 | 0.84 | KMT2A (0.70) | LMNAALDH1A1SMN1; SMN2KMT2AMEN1 | |
| SCHEMBL7681992 | 0.81 | SETD7 (0.66) | LMNASETD7ALDH1A1SMN1; SMN2KMT2A | |
| SCHEMBL7484708 | 0.79 | RXFP1 (0.61) | KMT2AMEN1RXFP1G6PDGAA | |
| SCHEMBL7483094 | 0.79 | CFTR (0.52) | LMNAALDH1A1SMN1; SMN2KMT2AMEN1 | |
| SCHEMBL7488047 | 0.79 | RXFP1 (0.57) | KMT2AMEN1RXFP1MAPTG6PD | |
| SCHEMBL7482392 | 0.77 | RXFP1 (0.58) | KMT2AMEN1RXFP1G6PDGAA | |
| SCHEMBL7478864 | 0.77 | MEN1 (0.67) | LMNAALDH1A1SMN1; SMN2KMT2AMEN1 | |
| SCHEMBL7486536 | 0.76 | KMT2A (0.61) | LMNAALDH1A1SMN1; SMN2KMT2AMEN1 | |
| SCHEMBL7482684 | 0.76 | ALDH1A1 (0.63) | LMNAALDH1A1SMN1; SMN2KMT2AMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1064273-B1 | 1,3,4-THIADIAZOLES USEFUL FOR THE TREATMENT OF CMV INFECTIONS | UPJOHN CO (US) | 2002-12-18 | — | — | EP | claimed |
| US-6150385-A | VIRICIDE WITH ACTIVITY AGAINST CYTOMEGALO VIRUS (CMV), HERPES VIRUS INCLUDING VARICELLA ZOSTER VIRUS, THE EPSTEIN-BARR VIRUS, THE HERPES SIMPLEX VIRUS, AND THE HUMAN HERPES VIRUS TYPE 8 (HHV-8) | PHARMACIA & UPJOHN COMPANY (US) | 2000-11-21 | — | — | US | claimed |
| EP-1064273-B1 | 1,3,4-THIADIAZOLES USEFUL FOR THE TREATMENT OF CMV INFECTIONS | UPJOHN CO (US) | 2002-12-18 | — | — | EP | disclosed |
| EP-1064273-A2 | 1,3,4-THIADIAZOLES USEFUL FOR THE TREATMENT OF CMV INFECTIONS | PHARMACIA & UPJOHN COMPANY (US) | 2001-01-03 | — | — | EP | disclosed |
| WO-1999047507-A2 | 1,3,4-THIADIAZOLES USEFUL FOR THE TREATMENT OF CMV INFECTIONS | PHARMACIA & UPJOHN COMPANY (US) | 1999-09-23 | — | — | WO | disclosed |