Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SETD7 | Q8WTS6 | 1/20 | 0.66 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.61 |
| ▸ | LMNA | P02545 | 3/20 | 0.61 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.61 |
| ▸ | MAPT | P10636 | 4/20 | 0.61 |
| ▸ | HPGD | P15428 | 2/20 | 0.61 |
| ▸ | MEN1 | O00255 | 3/20 | 0.60 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.60 |
| ▸ | HTT | P42858 | 1/20 | 0.59 |
| ▸ | GAA | P10253 | 1/20 | 0.59 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.59 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.58 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.57 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.57 |
| ▸ | RAB9A | P51151 | 1/20 | 0.57 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31546659 | 0.90 | ALDH1A1 (0.58) | SETD7ALDH1A1LMNATDP1MAPT | |
| SCHEMBL9550653 | 0.85 | SETD7 (0.53) | SETD7ALDH1A1LMNATDP1MAPT | |
| SCHEMBL12813280 | 0.85 | MMP13 (0.74) | ALDH1A1LMNAMAPTHPGDMEN1 | |
| SCHEMBL2838830 | 0.83 | MEN1 (0.61) | ALDH1A1LMNAMAPTHPGDMEN1 | |
| SCHEMBL5345965 | 0.82 | MMP13 (0.79) | ALDH1A1LMNAMAPTHPGDMEN1 | |
| SCHEMBL582322 | 0.81 | SMN1; SMN2 (0.85) | ALDH1A1LMNASMN1; SMN2ROCK2L3MBTL1 | |
| SCHEMBL7485285 | 0.81 | LMNA (0.63) | SETD7ALDH1A1LMNAMAPTMEN1 | |
| SCHEMBL1083633 | 0.80 | MEN1 (0.77) | ALDH1A1LMNAMAPTHPGDMEN1 | |
| SCHEMBL4156900 | 0.80 | ALDH1A1 (0.67) | ALDH1A1LMNAMAPTHPGDMEN1 | |
| SCHEMBL6940004 | 0.80 | GABRP (0.56) | ALDH1A1LMNAMAPTMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6384080-B1 | TREATMENT AND/OR PREVENTION OF CERTAIN CARDIOVASCULAR DISORDERS, UROGENITAL DISORDERS, RESPIRATORY SYSTEM DISORDERS, DISORDERS OF GUT MOTILITY, SEXUAL DISORDERS, DIABETIC COMPLICATIONS, URTICARIA | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2002-05-07 | — | — | US | disclosed |