Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 10/20 | 0.51 |
| ▸ | MEN1 | O00255 | 7/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 7/20 | 0.51 |
| ▸ | POLB | P06746 | 2/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.51 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.48 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.48 |
| ▸ | DRD2 | P14416 | 1/20 | 0.46 |
| ▸ | DRD3 | P35462 | 1/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 7/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.46 |
| ▸ | GAA | P10253 | 1/20 | 0.44 |
| ▸ | GPR55 | Q9Y2T6 | 1/20 | 0.44 |
| ▸ | RAB9A | P51151 | 8/20 | 0.43 |
| ▸ | NPC1 | O15118 | 6/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | MAOB | P27338 | 1/20 | 0.42 |
| ▸ | TP53 | P04637 | 1/20 | 0.42 |
| ▸ | THRB | P10828 | 1/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7485298 | 1.00 | MAPT (0.51) | MAPTMEN1KMT2APOLBALDH1A1 | |
| SCHEMBL7484285 | 0.87 | CYP3A4 (0.53) | MAPTMEN1KMT2APOLBALDH1A1 | |
| SCHEMBL7485346 | 0.87 | CYP3A4 (0.53) | MAPTMEN1KMT2APOLBALDH1A1 | |
| SCHEMBL7483528 | 0.83 | ITGB2 (0.51) | MAPTMEN1KMT2APOLBCYP3A4 | |
| SCHEMBL7483535 | 0.83 | ITGB2 (0.51) | MAPTMEN1KMT2APOLBCYP3A4 | |
| SCHEMBL7477866 | 0.82 | MAPT (0.50) | MAPTMEN1KMT2APOLBALDH1A1 | |
| SCHEMBL7477878 | 0.82 | MAPT (0.50) | MAPTMEN1KMT2APOLBALDH1A1 | |
| SCHEMBL7483102 | 0.81 | ITGB2 (0.51) | MAPTMEN1KMT2APOLBALDH1A1 | |
| SCHEMBL7485237 | 0.81 | ITGB2 (0.51) | MAPTMEN1KMT2APOLBALDH1A1 | |
| SCHEMBL7485669 | 0.80 | RAB9A (0.56) | MAPTMEN1KMT2APOLBCYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1064273-B1 | 1,3,4-THIADIAZOLES USEFUL FOR THE TREATMENT OF CMV INFECTIONS | UPJOHN CO (US) | 2002-12-18 | — | — | EP | claimed |
| US-6150385-A | VIRICIDE WITH ACTIVITY AGAINST CYTOMEGALO VIRUS (CMV), HERPES VIRUS INCLUDING VARICELLA ZOSTER VIRUS, THE EPSTEIN-BARR VIRUS, THE HERPES SIMPLEX VIRUS, AND THE HUMAN HERPES VIRUS TYPE 8 (HHV-8) | PHARMACIA & UPJOHN COMPANY (US) | 2000-11-21 | — | — | US | claimed |
| EP-1064273-B1 | 1,3,4-THIADIAZOLES USEFUL FOR THE TREATMENT OF CMV INFECTIONS | UPJOHN CO (US) | 2002-12-18 | — | — | EP | disclosed |
| EP-1064273-A2 | 1,3,4-THIADIAZOLES USEFUL FOR THE TREATMENT OF CMV INFECTIONS | PHARMACIA & UPJOHN COMPANY (US) | 2001-01-03 | — | — | EP | disclosed |
| WO-1999047507-A2 | 1,3,4-THIADIAZOLES USEFUL FOR THE TREATMENT OF CMV INFECTIONS | PHARMACIA & UPJOHN COMPANY (US) | 1999-09-23 | — | — | WO | disclosed |