Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR1A | P08908 | 3/20 | 0.50 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.45 |
| ▸ | CYP2D6 | P10635 | 3/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.45 |
| ▸ | GLA | P06280 | 2/20 | 0.45 |
| ▸ | HPGD | P15428 | 2/20 | 0.45 |
| ▸ | CASP1 | P29466 | 2/20 | 0.45 |
| ▸ | CASP7 | P55210 | 2/20 | 0.45 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.45 |
| ▸ | GAA | P10253 | 1/20 | 0.44 |
| ▸ | DRD2 | P14416 | 2/20 | 0.41 |
| ▸ | DRD1 | P21728 | 2/20 | 0.41 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.39 |
| ▸ | LMNA | P02545 | 2/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30666722 | 0.80 | HTR1A (0.49) | HTR1ACYP3A4ALDH1A1CYP2D6KDM4E | |
| SCHEMBL31754798 | 0.77 | HTR1A (0.46) | HTR1ACYP3A4ALDH1A1CYP2D6KDM4E | |
| SCHEMBL13585979 | 0.75 | FYN (0.50) | ALDH1A1KDM4EHSD17B10ADRA1AHIF1A | |
| SCHEMBL13747480 | 0.74 | HTR1A (0.43) | HTR1ACYP3A4ALDH1A1CYP2D6KDM4E | |
| SCHEMBL29991864 | 0.73 | TRPM5 (0.36) | — | |
| SCHEMBL12289080 | 0.72 | CYP3A4 (0.45) | HTR1ACYP3A4ALDH1A1CYP2D6KDM4E | |
| SCHEMBL9146774 | 0.71 | CYP3A4 (0.46) | HTR1ACYP3A4ALDH1A1CYP2D6KDM4E | |
| SCHEMBL29382485 | 0.71 | FYN (0.50) | HTR1ACYP3A4ALDH1A1CYP2D6KDM4E | |
| SCHEMBL5318502 | 0.71 | FYN (0.50) | HTR1ACYP3A4ALDH1A1CYP2D6KDM4E | |
| SCHEMBL9311203 | 0.70 | HTR1A (0.50) | HTR1ACYP3A4ALDH1A1CYP2D6KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0982305-B1 | Indane-1-ol derivatives, process for their preparation and pharmaceutical compositions containing them | SERVIER LAB (FR) | 2002-03-06 | — | — | EP | disclosed |
| US-6153625-A | Indan-1-ol compounds | ADIR ET COMPAGNIE (FR) | 2000-11-28 | — | — | US | disclosed |
| EP-0982305-A1 | Indane-1-ol derivatives, process for their preparation and pharmaceutical compositions containing them | ADIR ET COMPAGNIE (FR) | 2000-03-01 | — | — | EP | disclosed |