Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | CCR9 | P51686 | 2/20 | 0.37 |
| ▸ | ACSS2 | Q9NR19 | 1/20 | 0.34 |
| ▸ | KDM2B | Q8NHM5 | 5/20 | 0.33 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.33 |
| ▸ | CYP11B2 | P19099 | 3/20 | 0.33 |
| ▸ | CYP11B1 | P15538 | 2/20 | 0.33 |
| ▸ | CACNA2D1 | P54289 | 1/20 | 0.33 |
| ▸ | SCN7A | Q01118 | 1/20 | 0.32 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.32 |
| ▸ | RORC | P51449 | 1/20 | 0.32 |
| ▸ | PLA2G10 | O15496 | 1/20 | 0.32 |
| ▸ | PLA2G2A | P14555 | 1/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7485833 | 1.00 | ALDH1A1 (0.38) | ALDH1A1CCR9ACSS2KDM2BROCK2 | |
| SCHEMBL7494767 | 0.89 | KDM2B (0.35) | ALDH1A1CCR9KDM2BROCK2SCN7A | |
| SCHEMBL7494760 | 0.89 | KDM2B (0.35) | ALDH1A1CCR9KDM2BROCK2SCN7A | |
| SCHEMBL7488852 | 0.86 | CCR9 (0.39) | ALDH1A1CCR9ACSS2KDM2BROCK2 | |
| SCHEMBL7487473 | 0.85 | DPP4 (0.35) | ALDH1A1CCR9KDM2BKDM4ETSHR | |
| SCHEMBL7491392 | 0.83 | SLC6A4 (0.42) | ALDH1A1CCR9ACSS2ROCK2SCN7A | |
| SCHEMBL7491090 | 0.79 | HRH3 (0.36) | CCR9KDM2BROCK2SCN7AKCNH2 | |
| SCHEMBL7490741 | 0.79 | KDM2B (0.33) | CCR9KDM2BROCK2CYP11B2CYP11B1 | |
| SCHEMBL7490748 | 0.79 | KDM2B (0.33) | CCR9KDM2BROCK2CYP11B2CYP11B1 | |
| SCHEMBL7487436 | 0.78 | SCN7A (0.35) | ALDH1A1CCR9KDM2BROCK2SCN7A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0918768-B1 | AROMATIC AMIDINE DERIVATIVES USEFUL AS SELECTIVE THROMBIN INHIBITORS | C & C RES LAB (KR) | 2002-01-09 | — | — | EP | disclosed |
| US-6201006-B1 | ANTICOAGULANTS | C & C RESEARCH LABORATORIES (KR) | 2001-03-13 | — | — | US | disclosed |