Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DPP4 | P27487 | 5/20 | 0.35 |
| ▸ | KDM2B | Q8NHM5 | 3/20 | 0.33 |
| ▸ | CCR9 | P51686 | 2/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
| ▸ | PFKFB3 | Q16875 | 4/20 | 0.33 |
| ▸ | PFKFB2 | O60825 | 3/20 | 0.33 |
| ▸ | PFKFB1 | P16118 | 3/20 | 0.33 |
| ▸ | CTSC | P53634 | 1/20 | 0.33 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
| ▸ | TSHR | P16473 | 1/20 | 0.31 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7492809 | 0.90 | DPP4 (0.33) | DPP4CCR9PFKFB3PFKFB2PFKFB1 | |
| SCHEMBL7486877 | 0.88 | DPP4 (0.38) | DPP4CCR9PFKFB3PFKFB2PFKFB1 | |
| SCHEMBL7486885 | 0.88 | DPP4 (0.38) | DPP4CCR9PFKFB3PFKFB2PFKFB1 | |
| SCHEMBL7482932 | 0.87 | DPP4 (0.41) | DPP4PFKFB3PFKFB2PFKFB1SLC6A4 | |
| SCHEMBL7494337 | 0.87 | DPP4 (0.41) | DPP4PFKFB3PFKFB2PFKFB1SLC6A4 | |
| SCHEMBL7482926 | 0.87 | DPP4 (0.41) | DPP4PFKFB3PFKFB2PFKFB1SLC6A4 | |
| SCHEMBL7496050 | 0.87 | SLC6A4 (0.40) | DPP4ALDH1A1PFKFB3PFKFB2PFKFB1 | |
| SCHEMBL7441287 | 0.87 | SLC6A4 (0.40) | DPP4ALDH1A1PFKFB3PFKFB2PFKFB1 | |
| SCHEMBL7485835 | 0.85 | ALDH1A1 (0.38) | KDM2BCCR9ALDH1A1KDM4ETSHR | |
| SCHEMBL7485833 | 0.85 | ALDH1A1 (0.38) | KDM2BCCR9ALDH1A1KDM4ETSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0918768-B1 | AROMATIC AMIDINE DERIVATIVES USEFUL AS SELECTIVE THROMBIN INHIBITORS | C & C RES LAB (KR) | 2002-01-09 | — | — | EP | disclosed |
| US-6201006-B1 | ANTICOAGULANTS | C & C RESEARCH LABORATORIES (KR) | 2001-03-13 | — | — | US | disclosed |