Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OPRL1 | P41146 | 6/20 | 0.48 |
| ▸ | OPRM1 | P35372 | 5/20 | 0.48 |
| ▸ | SIRT2 | Q8IXJ6 | 1/20 | 0.48 |
| ▸ | OPRD1 | P41143 | 4/20 | 0.46 |
| ▸ | OPRK1 | P41145 | 4/20 | 0.46 |
| ▸ | CA12 | O43570 | 1/20 | 0.43 |
| ▸ | CA9 | Q16790 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9395606 | 0.95 | OPRL1 (0.48) | OPRL1OPRM1SIRT2OPRD1OPRK1 | |
| SCHEMBL8612151 | 0.86 | OPRL1 (0.48) | OPRL1OPRM1SIRT2OPRD1OPRK1 | |
| SCHEMBL8612024 | 0.83 | OPRL1 (0.48) | OPRL1OPRM1SIRT2OPRD1OPRK1 | |
| SCHEMBL8608985 | 0.83 | OPRL1 (0.46) | OPRL1OPRM1SIRT2OPRD1OPRK1 | |
| SCHEMBL8609291 | 0.83 | OPRL1 (0.48) | OPRL1OPRM1SIRT2OPRD1OPRK1 | |
| SCHEMBL8611525 | 0.82 | GRIK1 (0.57) | OPRL1OPRM1OPRD1OPRK1 | |
| SCHEMBL7481411 | 0.80 | OPRL1 (0.52) | OPRL1OPRM1OPRD1OPRK1 | |
| SCHEMBL8611345 | 0.80 | GRIK1 (0.57) | — | |
| SCHEMBL9395620 | 0.78 | SIRT2 (0.77) | OPRL1OPRM1SIRT2OPRD1OPRK1 | |
| SCHEMBL18203554 | 0.77 | SIRT2 (0.49) | OPRM1SIRT2OPRD1OPRK1CA12 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0799224-B1 | QUINOXALINES AND DRUGS PREPARED THEREFROM | BASF AG (DE) | 2002-04-17 | — | — | EP | disclosed |
| US-5852017-A | 2,3(1H,4H)-quinoxalinediones | BASF AKTIENGESELLSCHAFT (DE) | 1998-12-22 | — | — | US | disclosed |
| US-5849743-A | Quinoxalines and drugs prepared therefrom | BASF AKTIENGESELLSCHAFT (DE) | 1998-12-15 | — | — | US | disclosed |
| EP-0572852-B1 | Quinoxalin-2,3(1H,4H)-diones used as medicine | BASF AG (DE) | 1998-10-21 | — | — | EP | disclosed |
| US-5714489-A | 2,3(1H,4H)quinoxalinedione | BASF AKTIENGESELLSCHAFT (DE) | 1998-02-03 | — | — | US | disclosed |
| WO-1996019476-A1 | NOVEL QUINOXALINES AND DRUGS PREPARED THEREFROM | BASF AKTIENGESELLSCHAFT (DE) | 1996-06-27 | — | — | WO | disclosed |
| EP-0572852-A1 | Quinoxalin-2,3(1H,4H)-diones used as medicine | BASF Aktiengesellschaft (DE) | 1993-12-08 | — | — | EP | disclosed |