Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OPRL1 | P41146 | 5/20 | 0.48 |
| ▸ | OPRM1 | P35372 | 4/20 | 0.48 |
| ▸ | CA12 | O43570 | 1/20 | 0.46 |
| ▸ | CA9 | Q16790 | 1/20 | 0.46 |
| ▸ | SIRT2 | Q8IXJ6 | 1/20 | 0.46 |
| ▸ | OPRD1 | P41143 | 3/20 | 0.44 |
| ▸ | OPRK1 | P41145 | 3/20 | 0.44 |
| ▸ | PARP1 | P09874 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7486015 | 0.83 | OPRL1 (0.48) | OPRL1OPRM1CA12CA9SIRT2 | |
| SCHEMBL8612151 | 0.83 | OPRL1 (0.48) | OPRL1OPRM1SIRT2OPRD1OPRK1 | |
| SCHEMBL8611338 | 0.81 | OPRL1 (0.52) | OPRL1OPRM1OPRD1OPRK1PARP1 | |
| SCHEMBL8612024 | 0.81 | OPRL1 (0.48) | OPRL1OPRM1SIRT2OPRD1OPRK1 | |
| SCHEMBL9395606 | 0.81 | OPRL1 (0.48) | OPRL1OPRM1CA12CA9SIRT2 | |
| SCHEMBL8677797 | 0.80 | CA12 (0.41) | CA12CA9PARP1 | |
| SCHEMBL8677801 | 0.80 | CA12 (0.41) | CA12CA9PARP1 | |
| SCHEMBL8608985 | 0.80 | OPRL1 (0.46) | OPRL1OPRM1SIRT2OPRD1OPRK1 | |
| SCHEMBL8611525 | 0.79 | GRIK1 (0.57) | OPRL1OPRM1OPRD1OPRK1 | |
| SCHEMBL8608735 | 0.78 | GRIA1 (0.56) | OPRL1OPRM1OPRD1OPRK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5852017-A | 2,3(1H,4H)-quinoxalinediones | BASF AKTIENGESELLSCHAFT (DE) | 1998-12-22 | — | — | US | disclosed |
| EP-0572852-B1 | Quinoxalin-2,3(1H,4H)-diones used as medicine | BASF AG (DE) | 1998-10-21 | — | — | EP | disclosed |
| US-5714489-A | 2,3(1H,4H)quinoxalinedione | BASF AKTIENGESELLSCHAFT (DE) | 1998-02-03 | — | — | US | disclosed |
| EP-0572852-A1 | Quinoxalin-2,3(1H,4H)-diones used as medicine | BASF Aktiengesellschaft (DE) | 1993-12-08 | — | — | EP | disclosed |