Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SRD5A2 | P31213 | 1/20 | 0.62 |
| ▸ | HSD11B1 | P28845 | 7/20 | 0.62 |
| ▸ | POLB | P06746 | 2/20 | 0.61 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.61 |
| ▸ | NPC1 | O15118 | 1/20 | 0.56 |
| ▸ | RAB9A | P51151 | 1/20 | 0.56 |
| ▸ | HTR2A | P28223 | 1/20 | 0.54 |
| ▸ | HTR2C | P28335 | 1/20 | 0.54 |
| ▸ | HTR7 | P34969 | 1/20 | 0.54 |
| ▸ | HTR6 | P50406 | 1/20 | 0.54 |
| ▸ | MGLL | Q99685 | 1/20 | 0.54 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.54 |
| ▸ | GAA | P10253 | 1/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL662218 | 0.94 | HSD11B1 (0.64) | SRD5A2HSD11B1POLBALDH1A1HTR2A | |
| SCHEMBL31164032 | 0.90 | HSD11B1 (0.68) | HSD11B1POLBALDH1A1HTR2AHTR2C | |
| SCHEMBL662115 | 0.90 | HSD11B1 (0.68) | HSD11B1POLBALDH1A1HTR2AHTR2C | |
| Bicarbonate SCHEMBL11466272 | 0.86 | HSD11B1 (0.64) | HSD11B1POLBALDH1A1HTR2AHTR2C | |
| SCHEMBL8110383 | 0.83 | MEN1 (0.59) | HSD11B1POLBALDH1A1HTR2AHTR2C | |
| SCHEMBL9870334 | 0.83 | HSD11B1 (0.65) | HSD11B1POLBALDH1A1HTR2AHTR2C | |
| SCHEMBL7486159 | 0.82 | SRD5A2 (0.65) | SRD5A2POLBALDH1A1NPC1RAB9A | |
| SCHEMBL19762913 | 0.82 | NPC1 (0.53) | HSD11B1POLBALDH1A1NPC1RAB9A | |
| SCHEMBL9136087 | 0.82 | SRD5A2 (0.65) | SRD5A2POLBALDH1A1NPC1RAB9A | |
| SCHEMBL3440878 | 0.82 | NPC1 (0.53) | HSD11B1POLBALDH1A1NPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-102020726-B | Macromolecule difunctional group alpha-hydroxy-ketone photoinitiator and preparation method thereof | NEWSUN CO LTD | 2012-07-11 | — | — | CN | claimed |
| CN-102020726-A | Macromolecule difunctional group alpha-hydroxy-ketone photoinitiator and preparation method thereof | CHANGSHA XINYU HIGH POLYMER TECHNOLOGY CO LTD | 2011-04-20 | — | — | CN | claimed |
| CN-102020726-B | Macromolecule difunctional group alpha-hydroxy-ketone photoinitiator and preparation method thereof | NEWSUN CO LTD | 2012-07-11 | — | — | CN | disclosed |
| CN-102020726-A | Macromolecule difunctional group alpha-hydroxy-ketone photoinitiator and preparation method thereof | CHANGSHA XINYU HIGH POLYMER TECHNOLOGY CO LTD | 2011-04-20 | — | — | CN | disclosed |
| US-20050176792-A1 | Ketone substituted benzimidazole compounds | BOEHRINGER INGELHEIM PHARMACEUTICALS, INC. (US) | 2005-08-11 | — | — | US | disclosed |
| WO-2005070420-A1 | 1H-BENZIMIDAZOL-2-YL-BENZAMIDE DERIVATIVES AND RELATED COMPOUNDS AS ITK INHIBITORS (INTERLEUKIN-2-INDUCIBLE T CELL KINASE) FOR THE TREATMENT OF INFLAMMATION, IMMUNOLOGICAL AND ALLERGIC DISORDERS | BOEHRINGER INGELHEIM PHARMACEUTICALS, INC. (US) | 2005-08-04 | — | — | WO | disclosed |
| CN-1314906-A | Salts of paroxetine | SMITHKLINE BEECHAM PLC (GB) | 2001-09-26 | — | — | CN | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050176792-A1 | Ketone substituted benzimidazole compounds | ITK, BLK, BCKDK | SRD5A2 2313/4885HSD11B1 2303/4885POLB 2880/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.