Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TERT | O14746 | 1/20 | 0.36 |
| ▸ | STAT3 | P40763 | 1/20 | 0.34 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.34 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.32 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.32 |
| ▸ | ADORA2B | P29275 | 1/20 | 0.32 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.32 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.32 |
| ▸ | MAPT | P10636 | 2/20 | 0.32 |
| ▸ | HPGD | P15428 | 2/20 | 0.32 |
| ▸ | CDC25A | P30304 | 1/20 | 0.32 |
| ▸ | CDC25C | P30307 | 1/20 | 0.32 |
| ▸ | NPC1 | O15118 | 1/20 | 0.32 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.32 |
| ▸ | RAB9A | P51151 | 1/20 | 0.32 |
| ▸ | MPO | P05164 | 1/20 | 0.32 |
| ▸ | XDH | P47989 | 1/20 | 0.32 |
| ▸ | ERCC1 | P07992 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4959984 | 0.84 | ADORA3 (0.40) | TERTSTAT3HIF1AADORA3ADORA2A | |
| SCHEMBL7485274 | 0.72 | ADORA3 (0.33) | TERTADORA3ADORA2AADORA2BADORA1 | |
| SCHEMBL19062643 | 0.72 | TERT (0.33) | TERTSTAT3HIF1AADORA3ADORA2A | |
| SCHEMBL19062420 | 0.71 | TERT (0.33) | TERTSTAT3HIF1AADORA3ADORA2A | |
| SCHEMBL19062815 | 0.71 | TERT (0.33) | TERTSTAT3HIF1AADORA3ADORA2A | |
| SCHEMBL19199215 | 0.69 | CDC25A (0.34) | TERTSTAT3HIF1AADORA3ADORA2A | |
| SCHEMBL11976903 | 0.68 | RXFP1 (0.37) | TERTADORA3ADORA2AADORA2BADORA1 | |
| SCHEMBL11394064 | 0.67 | ERCC1 (0.61) | KDM4EALDH1A1HSD17B10HPGDMAPK1 | |
| SCHEMBL5879307 | 0.65 | CHEK1 (0.49) | ADORA3ADORA2AADORA2BADORA1KDM4E | |
| SCHEMBL13314453 | 0.64 | SRC (0.40) | ADORA2AADORA2BKDM4EALDH1A1HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1141140-B1 | NAPHTHALENEHYDRAZAMIMIDES AND PERYLENEHYDRAZAMIMIDES | CIBA SC HOLDING AG (CH) | 2002-09-04 | — | — | EP | disclosed |
| EP-1141140-A1 | NAPHTHALENEHYDRAZAMIMIDES AND PERYLENEHYDRAZAMIMIDES | Ciba SC Holding AG (CH) | 2001-10-10 | — | — | EP | disclosed |
| US-6143890-A | Naphthalenehydrazamimides and perylenehydrazamimides | CIBA SPECIALTY CHEMICALS CORPORATION (US) | 2000-11-07 | — | — | US | disclosed |
| WO-2000040657-A1 | NAPHTHALENEHYDRAZAMIMIDES AND PERYLENEHYDRAZAMIMIDES | CIBA SPECIALTY CHEMICALS HOLDING INC. (CH) | 2000-07-13 | — | — | WO | disclosed |