Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 3/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.37 |
| ▸ | THRB | P10828 | 1/20 | 0.37 |
| ▸ | ATM | Q13315 | 1/20 | 0.37 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.37 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | CA12 | O43570 | 2/20 | 0.35 |
| ▸ | CA1 | P00915 | 2/20 | 0.35 |
| ▸ | CA2 | P00918 | 2/20 | 0.35 |
| ▸ | CA9 | Q16790 | 1/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.34 |
| ▸ | RECQL | P46063 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7498634 | 0.95 | SMN1; SMN2 (0.37) | ALDH1A1MEN1KMT2ANPSR1CA12 | |
| SCHEMBL7494619 | 0.75 | EPHX1 (0.45) | ALDH1A1MEN1KMT2AEPHX1KDM4E | |
| SCHEMBL1170182 | 0.74 | TP53 (0.52) | ALDH1A1MEN1KMT2AL3MBTL1THRB | |
| SCHEMBL1169984 | 0.74 | TP53 (0.52) | ALDH1A1MEN1KMT2AL3MBTL1THRB | |
| SCHEMBL1169988 | 0.74 | TP53 (0.52) | ALDH1A1MEN1KMT2AL3MBTL1THRB | |
| SCHEMBL19321646 | 0.73 | TRPM8 (0.45) | ALDH1A1CA12CA1CA2CA9 | |
| SCHEMBL1030989 | 0.73 | CA1 (0.38) | ALDH1A1CA12CA1CA2CA9 | |
| SCHEMBL22869421 | 0.73 | TRPM8 (0.45) | ALDH1A1CA12CA1CA2CA9 | |
| SCHEMBL13748535 | 0.73 | TRPM8 (0.45) | ALDH1A1CA12CA1CA2CA9 | |
| SCHEMBL7486399 | 0.73 | SLC1A2 (0.44) | ALDH1A1MEN1KMT2AEPHX1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0771196-A4 | EXCITATORY AMINO ACID RECEPTOR ANTAGONISTS | LILLY CO ELI (US) | 1997-09-03 | — | — | EP | disclosed |
| EP-0771196-A1 | EXCITATORY AMINO ACID RECEPTOR ANTAGONISTS | ELI LILLY AND COMPANY (US) | 1997-05-07 | — | — | EP | disclosed |
| WO-1996007405-A1 | EXCITATORY AMINO ACID RECEPTOR ANTAGONISTS | ELI LILLY AND COMPANY (US) | 1996-03-14 | — | — | WO | disclosed |