SCHEMBL7487203

SCHEMBL7487203

BrCc1nc(-c2ccccc2)c(-c2ccccc2)o1

nearest known ligand 0.63

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
NR4A2 P43354 15/20 0.63
NR4A1 P22736 3/20 0.63
NR4A3 Q92570 3/20 0.63
AOC3 Q16853 1/20 0.60
RXRA P19793 7/20 0.59
RXRB P28702 6/20 0.59
RXRG P48443 4/20 0.59
KDM4E B2RXH2 1/20 0.59
ABCC4 O15439 1/20 0.59
C5 P01031 1/20 0.59
LMNA P02545 1/20 0.59
CHRM2 P08172 1/20 0.59
CYP3A4 P08684 1/20 0.59
CHRM1 P11229 1/20 0.59
DRD2 P14416 1/20 0.59
HPGD P15428 1/20 0.59
TSHR P16473 1/20 0.59
TBXA2R P21731 1/20 0.59
PTGS1 P23219 1/20 0.59
HTR2A P28223 1/20 0.59

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11719710 0.86 NR4A2 (0.65) NR4A2NR4A1NR4A3AOC3RXRA
SCHEMBL14867495 0.85 NR4A2 (0.73) NR4A2NR4A1NR4A3AOC3RXRA
SCHEMBL2760386 0.81 NR4A2 (0.63) NR4A2NR4A1NR4A3AOC3RXRA
SCHEMBL8929931 0.81 NR4A2 (0.68) NR4A2NR4A1NR4A3AOC3RXRA
SCHEMBL11718919 0.81 NR4A2 (0.63) NR4A2NR4A1NR4A3AOC3RXRA
SCHEMBL8446239 0.81 NR4A2 (0.68) NR4A2NR4A1NR4A3AOC3RXRA
SCHEMBL8113859 0.80 NR4A2 (0.66) NR4A2NR4A1NR4A3AOC3RXRA
Hydrochloric Acid SCHEMBL11714388 0.80 NR4A2 (0.61) NR4A2NR4A1NR4A3AOC3RXRA
SCHEMBL7492453 0.79 NR4A2 (0.66) NR4A2NR4A1NR4A3AOC3RXRA
SCHEMBL13653143 0.79 NR4A2 (0.65) NR4A2NR4A1NR4A3AOC3RXRA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 26 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-118344239-A Method for efficiently constructing carbon-carbon bond by nitrogen deletion reaction 南京大学 2024-07-16 CN claimed
CN-118344239-A Method for efficiently constructing carbon-carbon bond by nitrogen deletion reaction 南京大学 2024-07-16 CN disclosed
CN-118344239-A Method for efficiently constructing carbon-carbon bond by nitrogen deletion reaction 南京大学 2024-07-16 CN disclosed
US-8735398-B2 Hepatitis C virus inhibitors BRISTOL-MYERS SQUIBB COMPANY (US) 2014-05-27 US disclosed
US-8735398-B2 Hepatitis C virus inhibitors BRISTOL-MYERS SQUIBB COMPANY (US) 2014-05-27 US disclosed
US-20130085147-A1 Hepatitis C Virus Inhibitors BRISTOL-MYERS SQUIBB COMPANY (US) 2013-04-04 US disclosed
US-20130085147-A1 Hepatitis C Virus Inhibitors BRISTOL-MYERS SQUIBB COMPANY (US) 2013-04-04 US disclosed
US-8362020-B2 Hepatitis C virus inhibitors BRISTOL-MYERS SQUIBB COMPANY (US) 2013-01-29 US disclosed
US-8362020-B2 Hepatitis C virus inhibitors BRISTOL-MYERS SQUIBB COMPANY (US) 2013-01-29 US disclosed
US-20110294819-A1 Hepatitis C Virus Inhibitors BRISTOL-MYERS SQUIBB COMPANY 2011-12-01 US disclosed
US-5972965-A USEFUL FOR INHIBITION OF PLATELET AGGREGATION, VASODILATION, ANTIHYPERTENSIVE ACTIVITY AND PROSTAGLANDIN AGONIST FUJISAWA PHARMACEUTICAL CO., LTD. (JP) 1999-10-26 US disclosed
EP-0582164-B1 Adenosine re-uptake inhibiting derivatives of diphenyl oxazoles, thiazoles and imidazoles BRISTOL MYERS SQUIBB CO (US) 1998-12-23 EP disclosed
CN-1196726-A 4,5-diaryl oxazole derivatives FUJISAWA PHARMACEUTICAL CO (JP) 1998-10-21 CN disclosed
EP-0842161-A1 4,5-DIARYL OXAZOLE DERIVATIVES FUJISAWA PHARMACEUTICAL CO., LTD. (JP) 1998-05-20 EP disclosed
WO-1997003973-A1 4,5-DIARYL OXAZOLE DERIVATIVES FUJISAWA PHARMACEUTICAL CO., LTD. (JP) 1997-02-06 WO disclosed
US-5382584-A Antiischemic agents BRISTOL-MYERS SQUIBB COMPANY (US) 1995-01-17 US disclosed
US-5362879-A 4-5-diphenyloxazole derivatives as inhibitors of blood platelet aggregation BRISTOL-MYERS SQUIBB COMPANY (US) 1994-11-08 US disclosed
EP-0582164-A1 Adenosine re-uptake inhibiting derivatives of diphenyl oxazoles, thiazoles and imidazoles Bristol-Myers Squibb Company (US) 1994-02-09 EP disclosed
US-5262540-A FOR INHIBITION OF BLOOD PLATELET AGGREGATION IN MAMMALS BRISTOL-MYERS SQUIBB COMPANY (US) 1993-11-16 US disclosed
EP-0434034-A1 Oxazole derivatives Bristol-Myers Squibb Company (US) 1991-06-26 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20110294819-A1 Hepatitis C Virus Inhibitors HAVCR2, MAVS, GTF3C1 NR4A2 3701/4885NR4A1 3394/4885NR4A3 3140/4885
US-20130085147-A1 Hepatitis C Virus Inhibitors HAVCR2, MAVS, GTF3C1 NR4A2 3701/4885NR4A1 3394/4885NR4A3 3140/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.