Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR4A2 | P43354 | 14/20 | 0.68 |
| ▸ | NR4A1 | P22736 | 3/20 | 0.68 |
| ▸ | NR4A3 | Q92570 | 3/20 | 0.68 |
| ▸ | RXRA | P19793 | 8/20 | 0.64 |
| ▸ | RXRB | P28702 | 7/20 | 0.64 |
| ▸ | RXRG | P48443 | 4/20 | 0.64 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.64 |
| ▸ | ABCC4 | O15439 | 1/20 | 0.64 |
| ▸ | C5 | P01031 | 1/20 | 0.64 |
| ▸ | LMNA | P02545 | 1/20 | 0.64 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.64 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.64 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.64 |
| ▸ | DRD2 | P14416 | 1/20 | 0.64 |
| ▸ | HPGD | P15428 | 1/20 | 0.64 |
| ▸ | TSHR | P16473 | 1/20 | 0.64 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.64 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.64 |
| ▸ | HTR2A | P28223 | 1/20 | 0.64 |
| ▸ | HTR2C | P28335 | 1/20 | 0.64 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13653142 | 0.86 | NR4A2 (0.69) | NR4A2NR4A1NR4A3RXRARXRB | |
| SCHEMBL14867495 | 0.85 | NR4A2 (0.73) | NR4A2NR4A1NR4A3RXRARXRB | |
| SCHEMBL6026434 | 0.84 | PTGS2 (0.55) | NR4A2NR4A1NR4A3RXRARXRB | |
| SCHEMBL7502159 | 0.84 | PTGS2 (0.67) | NR4A2NR4A1NR4A3RXRARXRB | |
| SCHEMBL7501616 | 0.84 | PTGS2 (0.55) | NR4A2NR4A1NR4A3RXRARXRB | |
| SCHEMBL7502033 | 0.84 | PTGS2 (0.67) | NR4A2NR4A1NR4A3RXRARXRB | |
| SCHEMBL18063471 | 0.83 | NR4A2 (0.71) | NR4A2NR4A1NR4A3RXRARXRB | |
| SCHEMBL11718919 | 0.81 | NR4A2 (0.63) | NR4A2NR4A1NR4A3RXRARXRB | |
| SCHEMBL7487203 | 0.81 | NR4A2 (0.63) | NR4A2NR4A1NR4A3RXRARXRB | |
| SCHEMBL2760386 | 0.81 | NR4A2 (0.63) | NR4A2NR4A1NR4A3RXRARXRB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5605795-A | Assays using chemiluminescent, enzymatically cleavable substituted 1,2-dioxetanes and kits therefor | TROPIX, INC. (US) | 1997-02-25 | — | — | US | disclosed |
| US-5220005-A | Reactable with enzyme to release optically detectable energy | TROPIX, INC. (US) | 1993-06-15 | — | — | US | disclosed |