Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRIN2B | Q13224 | 7/20 | 0.36 |
| ▸ | JAK2 | O60674 | 1/20 | 0.35 |
| ▸ | JAK1 | P23458 | 1/20 | 0.35 |
| ▸ | TYK2 | P29597 | 1/20 | 0.35 |
| ▸ | JAK3 | P52333 | 1/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.34 |
| ▸ | LMNA | P02545 | 2/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | RAB9A | P51151 | 2/20 | 0.34 |
| ▸ | NPC1 | O15118 | 1/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6623462 | 0.97 | GRIN2B (0.38) | GRIN2BJAK2JAK1TYK2JAK3 | |
| SCHEMBL6623310 | 0.92 | L3MBTL1 (0.35) | GRIN2BJAK2JAK1TYK2JAK3 | |
| SCHEMBL5724018 | 0.78 | SMN1; SMN2 (0.51) | SMN1; SMN2ALDH1A1LMNAMAPTKMT2A | |
| SCHEMBL6622288 | 0.76 | L3MBTL1 (0.35) | GRIN2BJAK2JAK1TYK2JAK3 | |
| SCHEMBL5233372 | 0.73 | PREP (0.41) | L3MBTL1SMN1; SMN2ALDH1A1LMNAMAPT | |
| SCHEMBL6772807 | 0.73 | DPP8 (0.42) | L3MBTL1SMN1; SMN2ALDH1A1MAPTKMT2A | |
| SCHEMBL6623727 | 0.72 | L3MBTL1 (0.34) | GRIN2BL3MBTL1SMN1; SMN2ALDH1A1LMNA | |
| SCHEMBL5723978 | 0.72 | ALDH1A1 (0.47) | SMN1; SMN2ALDH1A1LMNAMAPTKMT2A | |
| SCHEMBL4476414 | 0.72 | ALDH1A1 (0.47) | SMN1; SMN2ALDH1A1LMNAMAPTKMT2A | |
| SCHEMBL5723982 | 0.72 | ALDH1A1 (0.47) | SMN1; SMN2ALDH1A1LMNAMAPTKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1251133-A1 | NOVEL CARBAPENEM DERIVATIVES | MEIJI SEIKA KAISHA LTD. (JP) | 2002-10-23 | — | — | EP | disclosed |